- Approval – Ensure all authors have seen and approved the final version of the article prior to submission and are aware it is being submitted to Reproduction and Fertility.
- Open access – The appropriate open-access option must be selected on submission. Authors are responsible for ensuring any funder mandates are followed. For further details, please see the open-access policy.
- Charges – Reproduction and Fertility is an open-access journal, and an article publication charge is payable upon acceptance. Full details are available on the publication charges page.
- Ethical compliance – All articles are required to meet the requirements outlined in our ethical policy. Ensure you have included all relevant ethical approval statements.
- Reported data – Data accuracy is crucial. Authors are strongly encouraged to double-check all reported data for accuracy and to confirm that all units of measurement are correct and consistent.
- Author list – All authors must be listed on the title page and entered on the ScholarOne Manuscripts submission in the correct order. Ensure all author email addresses provided are valid. Author information entered into ScholarOne Manuscripts will be used to generate PubMed listings for published papers.
- Cover letter – This letter should introduce your paper and outline why your work is important and suitable for publication at this time.
- English language – Non-native English speakers are encouraged to have their manuscript professionally edited before submission. See Bioscientifica’s recommended English language editing services. Manuscripts may be written in either UK or US English.
User account details
All submitting authors are required to link their ScholarOne account with their ORCID iD. The system will prompt the author to do this when creating the submission.
The journal also requests that all authors identified as ‘corresponding authors’ create and link an ORCID iD with their account on ScholarOne prior to article acceptance. We also encourage contributing authors to associate an ORCID iD with their ScholarOne account. Author ORCID iDs will be displayed on the published article.
Author email addresses
The journal requires an institutional email address is associated with the account of both the submitting author and corresponding author; please edit the associated ScholarOne accounts to include this before pressing 'submit'. Alternatively please provide an explanation as to why this is not available to the Editorial Office by contacting firstname.lastname@example.org
This policy has been adopted in order to verify the authenticity of article submissions and protect the integrity of Reproduction and Fertility.
- Please be aware that the combined size of your files should not exceed 40 MB.
- For article text: txt, doc, docx, rtf. We are unable to accept PDF files for article text for revised manuscripts, but can do so for first submissions.
- For figures: eps, tiff, jpg.
1. Title page
- Title (maximum 85 characters, including spaces)
- All authors' names and full addresses
- Corresponding author’s postal and email address
- A short title (maximum 46 characters, including spaces)
- A minimum of four keywords describing the manuscript
- Word count of the full article, excluding references and figure legends
3. Lay summary
- Justify your research.
- Give some context to the research and details about your findings and/or strategy used.
- Follow a logical order (this may not always coincide with a temporal order).
- Explain the impact of the work (especially in relation to wider society).
- Use short sentences and write in plain English (imagine that you are trying to explain your article to a family member who works e.g. in a bank).
- We encourage all authors to read a selection of lay summaries already published by R&F to appreciate the ways certain complex biological aspects can be make more accessible.
4. Graphical abstract
Font: Please use Arial, Helvetica, or courier in a font size of 8 pt.
Colour: Use of colour is encouraged. Colour figures should be in RGB format.
File Type: TIFF, JPG, EPS or PDF
6. Materials and methods
- Include the source of chemicals, reagents and hormones and give the manufacturer’s name in parentheses.
- Give the generic name, dose and route of administration for drugs.
- Specify the composition of buffers, solutions and culture media.
- Use SI symbols, give concentrations in mol/L and define the term % as w/v or v/v for all solutions. For international units use IU (U should be used for enzyme activity).
- Specify the type of equipment (microscopes/objective lenses, cameras, detectors) used to obtain images.
- RT-PCR methods should broadly follow the MIQE guidelines, see http://miqe.gene-quantification.info/ and Bustin et al 2009 Clin Chem 55:611-622.
- Methods for extracellular vesicle purification and characterisation should follow the guidelines set out in the MISEV guidelines, Théry et al 2018, doi.org/10.1080/20013078.2018.1535750.
- The EQUATOR network provides a database of reporting guidelines, aiming to improve the reliability of published health research literature by promoting transparent and accurate reporting. Authors may find this a useful resource.
- Specify any image acquisition software used, and give a description of specialized techniques requiring large amounts of processing, such as confocal, deconvolution, 3D reconstructions, or surface and volume rendering.
9. Declaration of interest, Funding, Contributions and Acknowledgements
Declaration of interest
Actual or perceived conflicts of interest for all authors must be declared in full.
Please either (a) declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported; or (b) fully declare any financial or other potential conflict of interest.
- Employment and consultancies
- Grants, fees and honoraria
- Ownership of stock or shares
- Patents (pending and actual)
- Board membership
Please detail all of the sources of funding relevant to the research reported in the following format:
This work was supported by the Medical Research Council (grant numbers xxxx, yyyy); the Wellcome Trust (grant number xxxx); and Tommy’s Baby charity (grant number xxxx).
This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.
Please include a statement concisely specifying the contribution of each co-author. Use author initials to indicate contributions, for example:
CP conceived the study and wrote the paper. GF performed experiments and analysed data.
Please be as brief as possible.
Any unpublished work (personal communications, manuscripts in preparation and manuscripts submitted but not yet accepted for publication) must be referred to in the text and not listed in the references.
(A Stone, J Brown & MR Smith, unpublished observations)
(J Brown, personal communication)
Cite references in the text using the authors’ names and publication year. Use et al. for articles with more than two authors. Where there are several citations, list them in chronological order.
List references in alphabetical order. Give articles by the same author in the order:
- Single author
- Two authors alphabetically according to the name of the second author
- Three or more authors chronologically, with a, b and c etc for articles published in the same year, in the order in which they are cited in the text
See RH, Calvo D, Shi Y, Kawa H, Luke MP & Yuan Z 2001 Stimulation of p300-mediated transcription by the kinase MEKK1. Journal of Biological Chemistry 276 16310–16317.
Harvey SS 1975 Hypnotics and sedatives. The barbiturates. In The Pharmacological Basis of Therapeutics, edn 5, pp 102–123. Eds LS Goodman & A Gilman. New York: Macmillan Publishing Co.
Please use Harvard style (Author, Year). Do not use an Endnote style which abbreviates the reference list in your submitted article.
- Number tables in the order they are cited in the text
- Include a title – a single sentence at the head of the table that includes the name of the organism studied
- Use footnotes to provide any additional explanatory material, cross-referenced to the column entries
- Give a short heading for each column
- Do not use internal horizontal or vertical lines, colour or shading
- Explain all abbreviations used in the table in the footnotes
- Number figures in the order they are cited in the text
- Include legends to all figures, giving the figure number, keys to any symbols used, the name of the organism studied, the names of any statistical tests used and the probability levels used for comparisons
- Label figure sections as A, B etc in the top left-hand corner
- Use Arial or a similar sans-serif font for text labels
- Do not enclose figures in boxes
- Indicate magnification by a scale bar in the bottom right-hand corner of the image and give the measurement in the legend
- Use the preferred symbols of closed and open circles, squares and triangles. Ensure that symbols are large enough to be read clearly when the figure is reduced for publication
- Use Courier or a similar non-proportional font for amino acid, DNA, RNA and PCR primer sequences and highlight sections of homology between sequences with grey shading
Reproduction and Fertility is committed to publishing high quality figures.
- Line images/graphs: EPS, TIFF, high-resolution PDF, AI (Adobe Illustrator). Resolution at final published size: 1200 dpi.
- Half-tone (greyscale) images: TIFF, high-resolution PDF, JPEG. Resolution at final published size: 600 dpi.
- Colour images: TIFF, high-resolution PDF, JPEG. EPS or AI files can be used for graphical data and illustrations that don’t include photographs. Resolution at final published size: 300 dpi. Colour format: CMYK (not RGB).
Research Letters are concise, focused reports of original research, in any of basic, translational, pre-clinical or clinical research. They can be sub-analyses or updates of previously published research, small studies and pilot studies. They should briefly summarise the results of original data. Reviews, case reports and opinion pieces are not considered for publication under this category.
Research Letters should not exceed 500 words (not counting the author information, references or legend) upon initial submission. Given the small maximum word count, they are not expected to contain detailed descriptions of methodological approaches used, nor extensive results or in-depth discussion, with results obtained using only one or two well-established methodologies.
Research Letters should have a maximum of 5 references, up to 1 table or figure/graph, and up to 5 authors. An abstract is not required; nor are specific sections (Introduction, Methods, Results, Discussion) needed. Authors are asked to include a Lay Summary, which will not count towards the 500 word limit (for full requirements see Research papers, Lay summary). Limited supplementary online content is allowed where absolutely necessary. Authors must meet all requirements regarding responsible conduct of research (e.g., appropriate IRB approval, data integrity, data retention). They should not be under consideration, submitted or published elsewhere in any form, in part or as whole.
Research letters are subject to peer review by an Associate Editor and at least one additional independent peer reviewer: the Editor(s)-in-Chief will make the final decision on publication.
Letters to the Editor
Letters comment on a Reproduction and Fertility article published within the last six months (referring to the online publication date) at the time of submission of the letter to Reproduction and Fertility.
A letter should not exceed a maximum word count of 1500 and should include a separate Title page with:.
- No title
- All author names (as they should appear in PubMed) – maximum of three authors
- Author affiliations
- Corresponding author’s postal and email address
- Maximum of three references
- Maximum of one figure or table
- No supplementary data
- Word count of the full article (maximum length 250 words, excluding references and figure legend).
The editors will judge if the letter is of interest, making a highly relevant point. In this case, the authors of the article that the letter comments upon will be invited to respond to the letter. If they choose to respond (same length of up to 250 words), letter and reply to letter will be published at the same time.
Publishing protocol papers helps to limit duplication of studies and increases transparency within research. The title should identify the article as a protocol.
Protocol manuscripts should report planned or ongoing research studies, in the area of basic or clinical reproductive biology/fertility. Reproduction and Fertility will not publish protocols of studies where data collection has been completed. Submitted protocols will be considered on a case-by-case basis and not all submitted protocols will be suitable for publication in the journal.
We ask that all submitted clinical trial protocols should be developed and reported according to SPIRIT guidelines. Papers are required to include the trial registration number, trial registration date and date of first patient’s enrolment.
(Supplementary Table 1)
(Supplementary Figures 1 and 2)
- Images taken from pathology slides
- Laparoscopic images
- Images of internal organs
- Ultrasound images
- Give the full binomial Latin names for all experimental animals other than common laboratory animals
- State the breed or strain and source of animals, and give details of age, weight, sex and housing
- Detail the procedures and anaesthetics used, including doses given
Experiments with genetically engineered mice
Authentication of cell lines
- Source of cell lines. Gifts of cell lines from individuals will not be acceptable
- Please state what the method of authentication is. For example, ATCC uses STRS analysis
- State the passage number(s) of cell lines used for the experiments described in the submission. Unless the research is specifically about senescence, lines >35 passages would not be acceptable.
Gene and protein nomenclature
- In gene and protein symbols, substitute Greek letters with the corresponding roman letter, eg TGFBR2 not TGFβR2
- Avoid hyphens unless they are part of the approved symbol, eg IGF1 not IGF-1
- Please use arabic rather than roman numerals, eg BMPR2 not BMPRII
Mice and rats
- Gene symbols should be in italics with only the first letter capitalised, eg Sox2
- Protein designations should be the same as the gene symbols except that all letters should be capitalised and in roman (ie not italicised), eg SOX2
- Please use symbols approved by the International Committee on Standardized Genetic Nomenclature for Mice and the Rat Genome and Nomenclature Committee, which can be queried at the MGI website.
Humans, non-human primates and domestic species
- Gene symbols should be in italics with all letters capitalised, eg SOX2
- Protein designations should be the same as the gene symbols but not italicised, eg SOX2
- Please use symbols approved by the HUGO Gene Nomenclature Committee (HGNC).
- Gene symbols should be in italics with all letters in lower case, eg sox2
- Protein designations should be the same as the gene symbols but not italicised and with the first letter capitalised, eg Sox2
- Please use symbols approved by the Zebrafish Nomenclature Committee (ZNC), which can be queried at the ZFIN website.
Digital image integrity
- No specific feature within an image may be enhanced, obscured, moved, removed or introduced. The groupings of images from different parts of the same gel, or from different gels, fields or exposures must be made explicit by the arrangement of the figure (eg using dividing lines) and in the text of the figure legend.
- Adjustments of brightness, contrast or colour balance are acceptable if and as long as they do not obscure or eliminate any information present in the original. Nonlinear adjustments (eg changes to gamma settings) must be disclosed in the figure legend. Adjustments should be applied to the entire image.
- Threshold manipulation, expansion or contraction of signal ranges and the altering of high signals should be avoided.
- Describe the numbers of experimental units used and the way in which they have been allocated to treatments
- Justify the omission of any observations from the analysis
- Describe methods of analysis precisely and state any necessary assumptions, as these may affect the conclusions that can be drawn from the experiment
Depositing data in public databases
Licence and Copyright
During the submission process the submitting author will need to complete a publication agreement on behalf of the co-authors and the copyright holder for the article. As part of this agreement, the copyright holder will grant the Society for Reproduction and Fertility and Bioscientifica a non-exclusive licence to publish the article. The copyright is retained by the original copyright holder and is not assigned to Society for Reproduction and Fertility or Bioscientifica.
Authors may download a copy of this agreement in advance.
Authors are entitled to appeal against a rejection decision made by a journal. Appeals should be submitted to the journal email address. We must receive your valid appeal within four weeks of the original decision, otherwise it will not be considered. An appeal is considered to be an extension of the peer review process and so you should not submit your article to another publication whilst an appeal is ongoing.
To be considered, appeals must directly address the reason(s) given for the initial rejection decision. If reviewer reports were included with the decision letter, then these criticisms must be responded to in the appeal, however you should not prepare and submit a revised version of your article with the appeal. Appeals that are received late, do not address reviewers’ criticisms, are dismissive of the reviewer comments, or contain offensive language will not be considered.
Valid appeals will be sent to a member of the journal’s Editorial Board for consideration. Where possible, an independent member of the Editorial Board who was not connected to the original decision will oversee the appeal.
If successful, an appeal may result in the decision being rescinded and a continuation of the peer-review process. If the appeal is rejected, then the original rejection decision is upheld and no further consideration of that article is possible.