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  • Author: Francesco Saverio Ludovichetti x
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Francesco Saverio Ludovichetti, Anna Giulia Signoriello, Edoardo Alvise Gobbato, Anna Artuso, Edoardo Stellini, and Sergio Mazzoleni

Periodontal health is today conceived as an integral part of systemic health itself and no longer as a single factor. Literature recognizes that the presence of periodontal disease can represent a risk factor for numerous systemic conditions such as heart disease and diabetes. In recent years we have witnessed a progressive interest regarding the influence exerted by this condition on the reproductive sphere, as well as on the possible repercussions on the conception possibilities. Following the analysis of the limited number of studies available for the correlation between periodontal disease and female infertility, it could be inferred that this condition can be equated to the presence of a real outbreak of infection and therefore exert its influence not only through bacterial translocation in the bloodstream, causing the systemic dissemination of pathogens, but also through the production of cytokines and immunoglobulins by inflammatory mediators. This situation limits bacteria growth, but it could cause damage to the fetus, to the reproductive system, and could invalidate conception attempts. Although many other studies and research are needed to better clarify the mechanism underlying the possible correlation between periodontal disease and female infertility, this article aims to review all the available literature concerning this topic.