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Elis Torrezan-Nitao, Hector Guidobaldi, Laura Giojalas, Christopher Barratt, and Stephen Publicover

Repetitive [Ca2+]i transients (oscillations), observed in progesterone (P4)-stimulated immobilised human sperm, reversibly modifiy flagellar beating. Here we report that such oscillations also occur in P4-stimulated free-swimming sperm and regulate (or contribute to) behavioural switching.