Search for other papers by Maria Dri in
Google Scholar
PubMed
Search for other papers by Francesca Gioia Klinger in
Google Scholar
PubMed
Search for other papers by Massimo De Felici in
Google Scholar
PubMed
, stimulating at the same time granulosa cell proliferation and reducing DNA fragmentation in such cells through the PI3K/Akt pathway. In this regard, it is worthy to mention that in a model of mouse gestational diabetes, the PMF formation in the ovaries of a
Search for other papers by Rachel T Cox in
Google Scholar
PubMed
Search for other papers by Joanna Poulton in
Google Scholar
PubMed
Search for other papers by Suzannah A Williams in
Google Scholar
PubMed
influence whether each fertilized egg will result in a healthy embryo are still not understood. The mature egg is the largest cell in the body, and the cytoplasm contains everything required for early embryo development apart from the paternal DNA
Search for other papers by Shen Chuen Khaw in
Google Scholar
PubMed
Search for other papers by Zhen Zhe Wong in
Google Scholar
PubMed
Search for other papers by Richard Anderson in
Google Scholar
PubMed
Search for other papers by Sarah Martins da Silva in
Google Scholar
PubMed
the production of malondialdehyde (MDA) and 4-hydroxynonenal (4HNE), which oxidises the lipid membrane and causes fragmentation of both nuclear and mitochondrial DNA in sperm ( de Lamirande & Gagnon 1992 , Kodama et al. 1997 , Gomez et al. 1998
Search for other papers by Roseanne Rosario in
Google Scholar
PubMed
The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia
Search for other papers by Wanyuan Cui in
Google Scholar
PubMed
Search for other papers by Richard A Anderson in
Google Scholar
PubMed
, niraparib, and talazoparib DNA repair including single-strand breaks, nucleotide excision repair, non-homologous end joining, homologous repair, and DNA mismatch repair Direct damage and death of primordial follicle oocytes, granulosa cell dysfunction
Search for other papers by G Hughes in
Google Scholar
PubMed
Reproductive Medicine Research Group, School of Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK
Search for other papers by S Martins da Silva in
Google Scholar
PubMed
.1186/s12915-021-00976-8 ) Bollwein H Fuchs I Koess C 2008 Interrelationship between plasma membrane integrity, mitochondrial membrane potential and DNA fragmentation in cryopreserved bovine spermatozoa . Reproduction in Domestic Animals 43 189
Search for other papers by Dimitra Apostolia Androni in
Google Scholar
PubMed
Search for other papers by Sophie Dodds in
Google Scholar
PubMed
School of Medicine, Division Child Health, Obstetrics and Gynaecology, Queen’s Medical Centre, Nottingham, UK
Search for other papers by Mathew Tomlinson in
Google Scholar
PubMed
Search for other papers by Walid E Maalouf in
Google Scholar
PubMed
Erkanli Şenturk G Ercan F 2017 Cryopreservation triggers DNA fragmentation and ultrastructural damage in spermatozoa of oligoasthenoteratozoospermic men . Marmara Medical Journal 30 63 – 72 . ( https://doi.org/10.5472/marumj.344797
Search for other papers by Valéria Barradas in
Google Scholar
PubMed
Search for other papers by Mariana Pereira Antoniassi in
Google Scholar
PubMed
Search for other papers by Paula Intasqui in
Google Scholar
PubMed
Search for other papers by Marcilio Nichi in
Google Scholar
PubMed
Hospital São Paulo, São Paulo, Brazil
Search for other papers by Ricardo Pimenta Bertolla in
Google Scholar
PubMed
Search for other papers by Deborah Montagnini Spaine in
Google Scholar
PubMed
testis of men with varicocele ( Fujisawa et al. 1999 ), which may have started in adolescence, as evidenced in a study that showed the presence of proteins with important role in DNA repair and promoting apoptosis (SMG1 and IBP3) exclusively in
Search for other papers by Beril Yuksel in
Google Scholar
PubMed
Search for other papers by Gonul Ozer in
Google Scholar
PubMed
Search for other papers by Ipek Nur Balin Duzguner in
Google Scholar
PubMed
Search for other papers by Aysu Akca in
Google Scholar
PubMed
Search for other papers by Yesim Kumtepe in
Google Scholar
PubMed
Search for other papers by Hakan Yelke in
Google Scholar
PubMed
Search for other papers by Semra Kahraman in
Google Scholar
PubMed
Search for other papers by George Liperis in
Google Scholar
PubMed
Search for other papers by Munevver Serdarogullari in
Google Scholar
PubMed
miscarriage rates, such as paternal age and sperm DNA fragmentation, will further highlight the importance of a holistic approach when consulting patients. In addition there is a lack on data on the number of miscarriages. With further validation, it would
Search for other papers by Steven Reynolds in
Google Scholar
PubMed
Search for other papers by Sarah J Calvert in
Google Scholar
PubMed
Search for other papers by Stephen J Walters in
Google Scholar
PubMed
Search for other papers by Martyn N Paley in
Google Scholar
PubMed
Search for other papers by Allan A Pacey in
Google Scholar
PubMed
.e. viability, morphology and DNA fragmentation, the method provides a means to creating sperm populations that differ in motility. In a previous study, we applied this method to normozoospermic ejaculates and measured the endogenous sperm metabolome of higher
Search for other papers by Noble K Kurian in
Google Scholar
PubMed
Search for other papers by Deepak Modi in
Google Scholar
PubMed
. Infection-associated inflammation can lead to elevated cytokine levels, collagen remodeling, and membrane weakening leading to preterm delivery. Surve et al. (2016) reported that membrane vesicles of GBS contributed to collagen fragmentation and membrane
