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Ola S Davis Reproductive Health and Biotechnology Lab, Department of Biomedical Sciences, OVC, University of Guelph, Guelph, Ontario, Canada

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Vivien B Truong Reproductive Health and Biotechnology Lab, Department of Biomedical Sciences, OVC, University of Guelph, Guelph, Ontario, Canada

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Katie D Hickey Department of Research and Development, Semex Alliance, Guelph, Ontario, Canada

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Laura A Favetta Reproductive Health and Biotechnology Lab, Department of Biomedical Sciences, OVC, University of Guelph, Guelph, Ontario, Canada

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research on their reproductive effects ( Catenza et al. 2021 ). While bisphenol production continues to increase, fertility rates among men are reportedly declining, with male factor contributing to 30-40% of infertility cases ( Practice Committee of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-23-0018
Volume/Issue:
Volume 4: Issue 4
Open access
Camila N Ortiz Department of Basic Sciences, Ponce Health Sciences University, Ponce Research Institute, Ponce, Puerto Rico, USA

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Annelyn Torres-Reverón DHR Health Institute for Research and Development, Edinburg, Texas, USA

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Caroline B Appleyard Department of Basic Sciences, Ponce Health Sciences University, Ponce Research Institute, Ponce, Puerto Rico, USA
Department of Internal Medicine, Ponce Health Sciences University, Ponce, Puerto Rico, USA

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, which is one of the limitations in research with human studies. Even though rodents do not have a menstrual cycle phase identical to humans, these models exhibit similar signs and symptoms experienced by human subjects, such as reduced fertility and

Article Type:
Review Article
Collections:
Clinical research and reviews
DOI:
https://doi.org/10.1530/RAF-20-0047
Volume/Issue:
Volume 2: Issue 2
Open access
Gabriel Maicas Australian Institute for Machine Learning, University of Adelaide, Adelaide, Australia

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Mathew Leonardi OMNI Gynaecological Ultrasound and Care, Sydney, Australia
Sydney Medical School Nepean, University of Sydney, Sydney, Australia
Department of Obstetrics and Gynecology, McMaster University, Hamilton, Canada

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Jodie Avery Robinson Research Institute, University of Adelaide, Adelaide, Australia

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Catrina Panuccio Specialist Imaging Partners, North Adelaide, Australia

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Gustavo Carneiro Australian Institute for Machine Learning, University of Adelaide, Adelaide, Australia

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M Louise Hull Robinson Research Institute, University of Adelaide, Adelaide, Australia
Discipline of Obstetrics and Gynaecology, Women & Children’s Hospital, Adelaide, Australia

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George Condous OMNI Gynaecological Ultrasound and Care, Sydney, Australia
Sydney Medical School Nepean, University of Sydney, Sydney, Australia

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ultrasound (TVS) test that is used to evaluate the POD ( Hudelist et al. 2013 , Reid et al. 2013 ). It can be interpreted by an ultrasound operator at the time of point-of-care scanning or by a radiologist/sonologist observing the recorded videos ( Chiu

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-21-0031
Volume/Issue:
Volume 2: Issue 4
Open access
C C Repelaer van Driel-Delprat Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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E W C M van Dam Division of Endocrinology, Department of Internal Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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P M van de Ven Department of Epidemiology and Biostatistics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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K Aissa Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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M K ter Haar Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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Y Feenstra Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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A de Roos Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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G Beelen Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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R Schats Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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C B Lambalk Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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hypothyroidism might lead to a disproportionally increased prevalence in subfertile women, likely contributing to overdiagnosis ( Reh et al. 2010 ) and a burden to the health care systems ( Dhillon-Smith et al. 2020 ). Therefore, the aim of this study was

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-20-0065
Volume/Issue:
Volume 2: Issue 4
Open access
Maria Dri Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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Francesca Gioia Klinger Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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Massimo De Felici Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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fertility ( Silvestris et al. 2019 ). It is known for a long time that metabolic disorders can cause ovarian dysfunctions and affect a woman’s fertility either by direct targeting follicular cells and/or the oocytes or by indirect interference with the

Article Type:
Review Article
DOI:
https://doi.org/10.1530/RAF-21-0038
Volume/Issue:
Volume 2: Issue 3
Open access
Samara Silva Souza Laboratory of Diagnostic Imaging Applied to Animal Reproduction, Faculty of Veterinary Medicine, State University of Ceara, Fortaleza, Ceara, Brazil

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Francisco Leo Nascimento Aguiar Department of Veterinary Medicine, Sousa Campus, Federal Institute of Education, Science and Technology of Paraíba, Sousa, Paraíba, Brazil

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Benner Geraldo Alves Laboratory of Manipulation of Oocytes and Preantral Follicles, Faculty of Veterinary Medicine, State University of Ceara, Fortaleza, Ceara, Brazil

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Kele Amaral Alves Laboratory of Manipulation of Oocytes and Preantral Follicles, Faculty of Veterinary Medicine, State University of Ceara, Fortaleza, Ceara, Brazil

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Fabiana Aparecida Santilli Brandão Laboratory of Diagnostic Imaging Applied to Animal Reproduction, Faculty of Veterinary Medicine, State University of Ceara, Fortaleza, Ceara, Brazil

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Danielle Cristina Calado Brito Laboratory of Manipulation of Oocytes and Preantral Follicles, Faculty of Veterinary Medicine, State University of Ceara, Fortaleza, Ceara, Brazil

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Ramon da Silva Raposo Nucleus of Experimental Biology, University of Fortaleza, Fortaleza, Ceara, Brazil

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Melba Oliveira Gastal Animal Science, School of Agricultural Sciences, Southern Illinois University, Carbondale, Illinois, USA

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Ana Paula Ribeiro Rodrigues Laboratory of Manipulation of Oocytes and Preantral Follicles, Faculty of Veterinary Medicine, State University of Ceara, Fortaleza, Ceara, Brazil

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José Ricardo Figueiredo Laboratory of Manipulation of Oocytes and Preantral Follicles, Faculty of Veterinary Medicine, State University of Ceara, Fortaleza, Ceara, Brazil

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Dárcio Ítalo Alves Teixeira Laboratory of Diagnostic Imaging Applied to Animal Reproduction, Faculty of Veterinary Medicine, State University of Ceara, Fortaleza, Ceara, Brazil

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Eduardo Leite Gastal Animal Science, School of Agricultural Sciences, Southern Illinois University, Carbondale, Illinois, USA

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Introduction Cryopreservation and ovarian tissue transplantation (OTT) have been successfully used to restore fertility in animal models ( Campbell et al. 2014 ) and women affected by reproductive impairment (for review, see Takae & Suzuki

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-21-0008
Volume/Issue:
Volume 2: Issue 4
Open access
Lysia Demetriou Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK

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Christian M Becker Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK

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Beatriz Martínez-Burgo Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK

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Adriana L Invitti Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK
Departamento de Ginecologia, Universidade Federal de São Paulo, São Paulo, Brazil

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Marina Kvaskoff Université Paris-Saclay, UVSQ, Univ. Paris-Sud, Inserm, Gustave Roussy, ‘Exposome and Heredity’ Team, CESP, Villejuif, France

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Razneen Shah Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK

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Emma Evans Oxford University Hospitals NHS Foundation Trust, Oxford, UK

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Claire E Lunde Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK
Biobehavioral Pediatric Pain Lab, Department of Psychiatry, Boston Children’s Hospital, Boston, Massachusetts, USA
Pain and Affective Neuroscience Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children’s Hospital, Massachusetts, USA

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Emma Cox Endometriosis UK, UK

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Kurtis Garbutt Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK

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Krina T Zondervan Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK
Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK

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Elaine Fox Department of Experimental Psychology, University of Oxford, Oxford, UK

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Katy Vincent Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK

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other specialists, delayed or cancelled surgical procedures and fertility treatments and difficulties accessing medication ( Yalçın Bahat et al. 2020 , Demetriou et al. 2021 ). Understanding the impact of the COVID-19 pandemic on those with

Article Type:
Research Article
Collections:
Endometriosis
DOI:
https://doi.org/10.1530/RAF-22-0028
Volume/Issue:
Volume 3: Issue 4
Open access
Janine Meuffels-Barkas Cryovault, Rhino Force SA NPC, Tokai, South Africa
Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa

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Sandra Wilsher The Paul Mellon Laboratory, Brunswick, Newmarket, Suffolk, UK

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W R Twink Allen The Paul Mellon Laboratory, Brunswick, Newmarket, Suffolk, UK

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Cyrillus Ververs VetRepSol, Rhenen, Utrechtsestraatweg, TW, The Netherlands

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Imke Lueders Cryovault, Rhino Force SA NPC, Tokai, South Africa
Mammal Research Institute, Faculty of Natural and Agricultural Sciences, University of Pretoria, Hatfield, South Africa

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difficulties. For example, genetically diverse mating partners may be located at different facilities in other countries or continents, and fertility may be sub-optimal when the social needs of captive animals are not met. The use of assisted reproductive

Article Type:
Review Article
Collections:
Fertility preservation, Wildlife
DOI:
https://doi.org/10.1530/RAF-23-0020
Volume/Issue:
Volume 4: Issue 3
Open access
Soo Young Baik Discovery and Translational Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom

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Alisha Maini Discovery and Translational Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom

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Haidee Tinning Discovery and Translational Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom

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Dapeng Wang LeedsOmics, University of Leeds, Leeds, United Kingdom
Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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Daman J Adlam Faculty of Biology, Medicine and Health, Division of Developmental Biology and Medicine, Maternal and Fetal Health Research Centre, School of Medical Sciences, Saint Mary’s Hospital, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK
Maternal and Fetal Health Research Centre, Saint Mary’s Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, UK

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Peter T Ruane Faculty of Biology, Medicine and Health, Division of Developmental Biology and Medicine, Maternal and Fetal Health Research Centre, School of Medical Sciences, Saint Mary’s Hospital, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK
Maternal and Fetal Health Research Centre, Saint Mary’s Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, UK

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Niamh Forde Discovery and Translational Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom

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stress ( Pham-Huy et al. 2008 ). Glutathione metabolism also may play a major role in fertility and endometrial function, as Xu et al. ( Xu et al. 2014 ) demonstrated that this pathway is crucial in reducing hydrogen peroxide (a type of reactive

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-21-0120
Volume/Issue:
Volume 4: Issue 2
Open access
Douglas A Gibson Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK

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Frances Collins Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK

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Bianca De Leo Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK
MRC Centre for Reproductive Health, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK

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Andrew W Horne MRC Centre for Reproductive Health, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK

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Philippa T K Saunders Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK

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, Roche, Nordic Pharma, and Abbvie. B D L is now an employee of Bayer AG Pharma, Preclinical Research. Andrew Horne is a Co-Editor-in-Chief of Reproduction and Fertility. Andrew Horne was not involved in the review or editorial process for this paper, on

Article Type:
Research Article
Collections:
Clinical research and reviews
DOI:
https://doi.org/10.1530/RAF-20-0072
Volume/Issue:
Volume 2: Issue 1
Open access