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Ola S Davis Reproductive Health and Biotechnology Lab, Department of Biomedical Sciences, OVC, University of Guelph, Guelph, Ontario, Canada

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Vivien B Truong Reproductive Health and Biotechnology Lab, Department of Biomedical Sciences, OVC, University of Guelph, Guelph, Ontario, Canada

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Katie D Hickey Department of Research and Development, Semex Alliance, Guelph, Ontario, Canada

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Laura A Favetta Reproductive Health and Biotechnology Lab, Department of Biomedical Sciences, OVC, University of Guelph, Guelph, Ontario, Canada

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research on their reproductive effects ( Catenza et al. 2021 ). While bisphenol production continues to increase, fertility rates among men are reportedly declining, with male factor contributing to 30-40% of infertility cases ( Practice Committee of

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G Hughes Assisted Conception Unit, Ninewells Hospital, Dundee, UK

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S Martins da Silva Assisted Conception Unit, Ninewells Hospital, Dundee, UK
Reproductive Medicine Research Group, School of Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK

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infertile men appear to be more vulnerable to cryodamage compared to gametes from fertile men ( Donnelly et al. 2001 ). Yet, the wider implications of cryopreservation on sperm quality and function are not completely understood. Cryopreservation has been

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C C Repelaer van Driel-Delprat Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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E W C M van Dam Division of Endocrinology, Department of Internal Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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P M van de Ven Department of Epidemiology and Biostatistics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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K Aissa Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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M K ter Haar Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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Y Feenstra Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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A de Roos Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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G Beelen Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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R Schats Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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C B Lambalk Division of Reproductive Medicine, Department of Obstetrics, Gynaecology and Reproductive Medicine, Amsterdam Reproduction & Development, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

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Y Li J Li X Liu H Liang X 2018 Egg quality and pregnancy outcome in young infertile women with diminished ovarian reserve . Medical Science Monitor 24 7279 – 7284 . ( https://doi.org/10.12659/MSM.910410 ) 30310048 Cramer DW Sluss PM

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Maria Dri Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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Francesca Gioia Klinger Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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Massimo De Felici Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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Introduction Metabolic syndrome and infertility are two disorders with a high prevalence in the general population. This syndrome comprises distinct metabolic risk factors including obesity, hyperglycaemia, hypertriglyceridemia, hypertension

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Kaltrina Krasniqi Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK

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Naomi Black Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK
University Hospitals Coventry and Warwickshire, Coventry, UK

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Erin J Williams MRC Centre for Reproductive Health & The Roslin Institute, University of Edinburgh, College of Medicine and Veterinary Medicine, Edinburgh, UK

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Osvaldo Bogado Pascottini Department of Internal Medicine, Reproduction and Population Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

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Sarah Thornton Hook Norton Veterinary Group, White Hill Surgery, Hook Norton, UK

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Siobhan Quenby Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK
University Hospitals Coventry and Warwickshire, Coventry, UK

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Joshua Odendaal Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK
University Hospitals Coventry and Warwickshire, Coventry, UK

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referred to as cytological endometritis. For the purposes of this review SCE refers to both SCE and cytological endometritis. SCE is the cause of infertility in an estimated 15–67% of dairy cows, and each case causes significant financial burden due to the

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Jennifer Dabel Institute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Muenster, Germany

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Florian Schneider Institute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Muenster, Germany
Department of Clinical Andrology, Centre of Reproductive Medicine and Andrology, Muenster, Germany

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Joachim Wistuba Institute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Muenster, Germany

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Sabine Kliesch Department of Clinical Andrology, Centre of Reproductive Medicine and Andrology, Muenster, Germany

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Stefan Schlatt Institute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Muenster, Germany

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Nina Neuhaus Institute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Muenster, Germany

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Introduction Fertility preservation is recommended for patients who are at risk of infertility due to disease or gonadotoxic treatment. After the onset of puberty and initiation of spermatogenesis, cryopreservation of sperm can be offered as a

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E Scott Sills Office for Reproductive Research, Center for Advanced Genetics/FertiGen, San Clemente, California, USA
Regenerative Biology Group, Fertility Reserve Bank San Clemente, California, USA

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Samuel H Wood Gen 5 Fertility Center, San Diego, California, USA

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rejuvenation’ by injection into older or non-responsive ovaries. This matters because, for now, hormone replacement and in vitro fertilization/egg donation are the only available clinical treatment options for menopause and infertility. Although the gradual

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Sarah McCredie School of Women’s and Children’s Health, UNSW Medicine, UNSW, New South Wales, Australia

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Belinda An School of Women’s and Children’s Health, UNSW Medicine, UNSW, New South Wales, Australia

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Monika McShane Royal Hospital for Women, Randwick, New South Wales, Australia

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William Ledger School of Women’s and Children’s Health, UNSW Medicine, UNSW, New South Wales, Australia
Royal Hospital for Women, Randwick, New South Wales, Australia

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Christos A Venetis School of Women’s and Children’s Health, UNSW Medicine, UNSW, New South Wales, Australia
Royal Hospital for Women, Randwick, New South Wales, Australia

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.9 History of infertility 2  No 38 84.4  Yes 3 6.7 Assisted conception 1  No 40 88.9  Yes 2 4.4 Smoking 1  No 41 91.1  Yes 1 2.2 Alcohol

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Lisa Windhofer Institute of in vivo and in vitro Models, University of Veterinary Medicine Vienna, Vienna, Austria

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Auke Boersma Institute of in vivo and in vitro Models, University of Veterinary Medicine Vienna, Vienna, Austria

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Maik Dahlhoff Institute of in vivo and in vitro Models, University of Veterinary Medicine Vienna, Vienna, Austria

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Thomas Rülicke Department for Biomedical Sciences, University of Veterinary Medicine, Vienna, Austria

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Kerstin E Auer Institute of in vivo and in vitro Models, University of Veterinary Medicine Vienna, Vienna, Austria

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medicine to overcome infertility problems in cases of obstructive and non-obstructive azoospermia ( Craft et al. 1995 , Collins et al. 1996 , Meniru et al. 1998 , Glina et al. 2003 , Esteves et al. 2011 , Jensen et al. 2016 , Hao et al

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W G Foster Department of Obstetrics & Gynecology, McMaster University, Hamilton, Ontario, Canada

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M Leonardi Department of Obstetrics & Gynecology, McMaster University, Hamilton, Ontario, Canada

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variable and dependent on the tissue on which it grows. Hallmark features of endometriosis include pelvic pain and infertility; however, some people with endometriosis remain asymptomatic. Endometriosis is a disease whose impact on the health care system

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