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Paediatric Oncology, Leeds Children’s Hospital, Leeds, UK
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futures There are two linked arguments to consider here, one centred on FP providing hope for a future and the other on an imagined future as a parent. Hope for a future It is well evidenced that the experience of infertility can lead to distress
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a hormonal treatment (H). (F) The abundance of CD14 high or CD14 low peritoneal macrophages (PMφ) did not differ between women reporting infertility (True) and those who did not (False). (G) The abundance of CD14 high or CD14 low PMφ in women
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1984 and provided the first guidance for the UK government on the ethics surrounding infertility treatments and research on human embryos ( Warnock 1984 ). This advised the government on the regulation of these fields, ensuring that laws passed were
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Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
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, painful intercourse, and infertility; however, non-specific symptoms often accompany these more prominent features. Treatments in the domains of medical management, surgery, and alternative management can be effective for many if used optimally but may not
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://doi.org/10.1002/mrd.1052 ). 11468782 Collodel G Castellini C Iacoponi F Noto D Signorini C 2020 Cytosolic phospholipase A(2) and F(2) isoprostanes are involved in semen quality and human infertility: a study on leucocytospermia, varicocele and
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leads to symptoms such as infertility and gynaecomastia ( Los & Ford 2023 ) ( Fukami 2023 ). Despite this, a person with Klinefelter’s syndrome is generally phenotypically male and is identified as such. A person with Turner’s syndrome (45 X0 karyotype
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( Sullivan et al. 2013 ). Given the critical contribution of EVs to gamete function, it is perhaps not surprising that their dysregulation is linked with infertility ( Stegmayr et al. 1982 , Carlsson et al. 2004 , Park et al. 2011 , Bai et al
Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, USA
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Frequency of pregnancy failure Infertility is a common problem in reproductive health. Maximal fertility in women trying to conceive is only 30% per cycle ( Zinaman et al. 1996 , Bonde et al. 1998 ). Wilcox et al. (1988) found that 22
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). Meanwhile, elevated levels of NEFA were also observed in women with high BMI values and obesity ( Valckx et al. 2014 b ); and FA concentrations in FF and infertility rates were positively correlated to increased BMI. A high-fat diet can also modify NEFA
Jean Hailes for Women’s Health, Melbourne, Victoria, Australia
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. 2007 , Agarwal et al. 2019 , Armour et al. 2022 ). Pain and infertility significantly impacting the quality of life are the most common symptoms of endometriosis. Endometriosis has a high individual and societal burden costing an estimated $6