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Charlotte Pickett Department of Obstetrics, Gynecology and Reproductive Sciences, Center for Endometriosis Research and Treatment, UC San Diego, La Jolla, California, USA

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Warren G Foster Department of Obstetrics, Gynecology and Reproductive Sciences, Center for Endometriosis Research and Treatment, UC San Diego, La Jolla, California, USA
McMaster University Health Sciences Center, Hamilton, Ontario, Canada

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Sanjay K Agarwal Department of Obstetrics, Gynecology and Reproductive Sciences, Center for Endometriosis Research and Treatment, UC San Diego, La Jolla, California, USA

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Introduction Endometriosis is a chronic disease associated with debilitating pain that affects at least 6–10% of reproductive age women and people assigned female at birth, independent of whether they identify as female ( Fuldeore & Soliman

Article Type:
Review Article
Collections:
Endometriosis
DOI:
https://doi.org/10.1530/RAF-22-0091
Volume/Issue:
Volume 4: Issue 3
Open access
Peter Thiel Department of Obstetrics and Gynecology, University of Saskatchewan College of Medicine, Regina, Saskatchewan, Canada

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Matthew J Burke Neuropsychiatry Program, Department of Psychiatry and Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

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Philippa Bridge-Cook The Endometriosis Network Canada, Toronto, Ontario, Canada

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Mathew Leonardi Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada

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, which leaves the treatment of endometriosis especially susceptible to their effects ( Colloca & Barsky 2020 ). Endometriosis is characterized by endometrium-like tissue outside the uterine cavity. It classically presents as cyclical pelvic pain

Article Type:
Discussion
Collections:
Endometriosis
DOI:
https://doi.org/10.1530/RAF-21-0040
Volume/Issue:
Volume 2: Issue 4
Open access
Mike Armour NICM Health Research Institute, Western Sydney University, Sydney, New South Wales, Australia
Translational Health Research Institute (THRI), Western Sydney University, Sydney, New South Wales, Australia
Medical Research Institute of New Zealand (MRINZ), Wellington, New Zealand

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Jodie Avery Robinson Research Institute, Adelaide Medical School, University of Adelaide, Adelaide, Australia

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Mathew Leonardi Robinson Research Institute, Adelaide Medical School, University of Adelaide, Adelaide, Australia

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Leesa Van Niekerk School of Psychological Sciences, University of Tasmania, Hobart, Tasmania, Australia

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Marilla L Druitt University Hospital Geelong, Deakin University, Victoria, Australia

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Melissa A Parker Canberra Endometriosis Centre, Department of Obstetrics and Gynaecology, ACT Health, Canberra ACT, Australia

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Jane E Girling Department of Anatomy, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand

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Brett McKinnon Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland, Australia

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Antonina Mikocka-Walus Centre for Social and Early Emotional Development, School of Psychology, Deakin University, Geelong, Australia

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Cecilia H M Ng Jean Hailes for Women’s Health, Melbourne, Victoria, Australia
School of Women’s and Children’s Health, University of New South Wales, Sydney, New South Wales, Australia

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Rebecca O’Hara Robinson Research Institute, Adelaide Medical School, University of Adelaide, Adelaide, Australia

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Donna Ciccia NICM Health Research Institute, Western Sydney University, Sydney, New South Wales, Australia
Endometriosis Australia, Sydney, Australia

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Katherine Stanley Endo Help Foundation, Victoria, Australia

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Subhadra Evans Centre for Social and Early Emotional Development, School of Psychology, Deakin University, Geelong, Australia

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Introduction As researchers and clinicians are working to improve the lives of those with endometriosis, this piece aims to highlight the significant financial burden experienced by the large number of affected individuals in our communities

Article Type:
Article Commentary
DOI:
https://doi.org/10.1530/RAF-22-0003
Volume/Issue:
Volume 3: Issue 3
Open access
Qian Feng Oxford Endometriosis CaRe Centre, Nuffield Department of Women’s and Reproductive Health, University of Oxford, John Radcliffe Hospital, Women’s Centre, Oxford, United Kingdom
Department of Obstetrics and Gynaecology, Monash University, Melbourne, Clayton, Victoria, Australia

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Nina Shigesi Oxford Endometriosis CaRe Centre, Nuffield Department of Women’s and Reproductive Health, University of Oxford, John Radcliffe Hospital, Women’s Centre, Oxford, United Kingdom

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Jun Guan Department of Gynaecology, Obstetrics and Gynaecology Hospital of Fudan University, Shanghai, China

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Nilufer Rahmioglu Oxford Endometriosis CaRe Centre, Nuffield Department of Women’s and Reproductive Health, University of Oxford, John Radcliffe Hospital, Women’s Centre, Oxford, United Kingdom
Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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Mona Bafadhel School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, Guy’s Campus, King’s College London, United Kingdom

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Kevin Paddon Laboratory Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom

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Carol Hubbard Oxford Endometriosis CaRe Centre, Nuffield Department of Women’s and Reproductive Health, University of Oxford, John Radcliffe Hospital, Women’s Centre, Oxford, United Kingdom

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Krina T Zondervan Oxford Endometriosis CaRe Centre, Nuffield Department of Women’s and Reproductive Health, University of Oxford, John Radcliffe Hospital, Women’s Centre, Oxford, United Kingdom
Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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Christian M Becker Oxford Endometriosis CaRe Centre, Nuffield Department of Women’s and Reproductive Health, University of Oxford, John Radcliffe Hospital, Women’s Centre, Oxford, United Kingdom

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Karin Hellner Oxford Endometriosis CaRe Centre, Nuffield Department of Women’s and Reproductive Health, University of Oxford, John Radcliffe Hospital, Women’s Centre, Oxford, United Kingdom

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Introduction Endometriosis is a chronic inflammatory disease characterized by the presence of endometrium-like tissue outside of the uterus, affecting about one in ten women during their reproductive age ( Bulun 2009 , Zondervan et al. 2020

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-23-0090
Volume/Issue:
Volume 5: Issue 3
Open access
Lysia Demetriou Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK

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Christian M Becker Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK

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Beatriz Martínez-Burgo Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK

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Adriana L Invitti Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK
Departamento de Ginecologia, Universidade Federal de São Paulo, São Paulo, Brazil

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Marina Kvaskoff Université Paris-Saclay, UVSQ, Univ. Paris-Sud, Inserm, Gustave Roussy, ‘Exposome and Heredity’ Team, CESP, Villejuif, France

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Razneen Shah Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK

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Emma Evans Oxford University Hospitals NHS Foundation Trust, Oxford, UK

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Claire E Lunde Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK
Biobehavioral Pediatric Pain Lab, Department of Psychiatry, Boston Children’s Hospital, Boston, Massachusetts, USA
Pain and Affective Neuroscience Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children’s Hospital, Massachusetts, USA

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Emma Cox Endometriosis UK, UK

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Kurtis Garbutt Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK

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Krina T Zondervan Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK
Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK

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Elaine Fox Department of Experimental Psychology, University of Oxford, Oxford, UK

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Katy Vincent Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK

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Introduction Endometriosis is a chronic condition that affects ~10% of women globally. It is classically associated with a variety of pelvic pain syndromes and subfertility; however, many sufferers also describe heavy periods and tiredness

Article Type:
Research Article
Collections:
Endometriosis
DOI:
https://doi.org/10.1530/RAF-22-0028
Volume/Issue:
Volume 3: Issue 4
Open access
Ezekiel O Mecha Department of Biochemistry, University of Nairobi, Nairobi, Kenya

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Joseph N Njagi Marple Grove Gynecological Centre, Kerugoya, Kenya

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Roselydiah N Makunja Department of Biochemistry, University of Nairobi, Nairobi, Kenya

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Charles O A Omwandho Department of Biochemistry, University of Nairobi, Nairobi, Kenya
Kirinyaga University, Kerugoya, Kenya

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Philippa T K Saunders EXPPECT Centre, Queen’s Medical Research Institute, Edinburgh Bioquarter, The University of Edinburgh, Edinburgh, UK

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Andrew W Horne EXPPECT Centre, Queen’s Medical Research Institute, Edinburgh Bioquarter, The University of Edinburgh, Edinburgh, UK

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Key points The prevalence of endometriosis in women in Africa is unknown. Women in Africa with symptoms caused by endometriosis experience barriers to diagnosis. Development and implementation of treatments suitable for African

Article Type:
Article Commentary
DOI:
https://doi.org/10.1530/RAF-22-0040
Volume/Issue:
Volume 3: Issue 3
Open access
Carlos H Miyashira Centro de Ensaios Clinicos, Fundação Butantan, São Paulo, Sao Paulo, Brazil

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Fernanda Reali Oliveira Departamento de Obstetricia e Ginecologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil

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Marina Paula Andres Departamento de Obstetricia e Ginecologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil
Gynecologic Division, BP – A Beneficencia Portuguesa de Sao Paulo, Sao Paulo, Sao Paulo, Brazil

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Julian A Gingold OB/GYN and Women’s Health, Division of Reproductive Endocrinology and Infertility, Montefiore Medical Center, Bronx, New York, USA

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Mauricio Simões Abrão Departamento de Obstetricia e Ginecologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil
Gynecologic Division, BP – A Beneficencia Portuguesa de Sao Paulo, Sao Paulo, Sao Paulo, Brazil

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Introduction Endometriosis is a multi-factorial disease defined by the presence of endometrial stroma or glands outside the uterine cavity. Patients with endometriosis, representing approximately 10–15% of reproductive-aged women, commonly

Article Type:
Review Article
Collections:
Endometriosis
DOI:
https://doi.org/10.1530/RAF-21-0113
Volume/Issue:
Volume 3: Issue 3
Open access
Camila N Ortiz Department of Basic Sciences, Ponce Health Sciences University, Ponce Research Institute, Ponce, Puerto Rico, USA

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Annelyn Torres-Reverón DHR Health Institute for Research and Development, Edinburg, Texas, USA

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Caroline B Appleyard Department of Basic Sciences, Ponce Health Sciences University, Ponce Research Institute, Ponce, Puerto Rico, USA
Department of Internal Medicine, Ponce Health Sciences University, Ponce, Puerto Rico, USA

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Introduction Endometriosis (EMT) is a chronic inflammatory disease characterized by the presence of endometrial-like glands and stroma that can be present within the peritoneal cavity, ovaries, rectovaginal septum, fossa ovarica, uterosacral

Article Type:
Review Article
Collections:
Clinical research and reviews
DOI:
https://doi.org/10.1530/RAF-20-0047
Volume/Issue:
Volume 2: Issue 2
Open access
Olga Bougie Department of Obstetrics and Gynaecology, Queen’s University, Kingston, Ontario, Canada

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Ikunna Nwosu School of Medicine, Queen’s University, Kingston, Ontario, Canada

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Chelsie Warshafsky Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada

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Introduction Endometriosis is a chronic, multisystemic disease of inflammation affecting approximately 10% of the female population ( Eskenazi & Warner 1997 , Zondervan et al. 2018 , 2020 ). It is defined as the extra-uterine growth of

Article Type:
Review Article
Collections:
Endometriosis
DOI:
https://doi.org/10.1530/RAF-21-0106
Volume/Issue:
Volume 3: Issue 2
Open access
Douglas A Gibson Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK

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Frances Collins Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK

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Bianca De Leo Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK
MRC Centre for Reproductive Health, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK

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Andrew W Horne MRC Centre for Reproductive Health, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK

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Philippa T K Saunders Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK

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Introduction Endometriosis is a chronic neuroinflammatory condition affecting ~180 million women worldwide and has a socioeconomic impact similar to diabetes ( Horne & Saunders 2019 ). It is defined by the presence of endometrial-like tissue

Article Type:
Research Article
Collections:
Clinical research and reviews
DOI:
https://doi.org/10.1530/RAF-20-0072
Volume/Issue:
Volume 2: Issue 1
Open access