). Cigarette smoke is composed of over 4000 different chemicals ( Richter et al. 2008 ), many of which can have harmful effects on the developing ovary. Of these, one of the components on which there is the most evidence of toxicological effects is benzo
Agnes Stefansdottir, Magda Marečková, Magdalena Matkovic, Caroline M Allen, and Norah Spears
Menghe Liu, Katja Hummitzsch, Nicole A Bastian, Monica D Hartanti, Helen F Irving-Rodgers, Richard A Anderson, and Raymond J Rodgers
Introduction Polycystic ovary syndrome (PCOS) is one of the most prevalent endocrine disorders, affecting approximately 10% of women of reproductive age ( March et al. 2010 , Bozdag et al. 2016 ). Women with PCOS are identified with
Heidy Kaune, Juan F Montiel, Mark Fenwick, and Suzannah A Williams
smaller litter of around 50% of controls and then becoming unable to produce subsequent litters ( Williams et al. 2007 ). With increasing age, ovarian morphology exhibits increasingly aberrant follicle development, and by 3 months of age, DM ovaries
Roseanne Rosario, Wanyuan Cui, and Richard A Anderson
-cancer therapies on gonadal function, and a recent review discussing the effect of chemotherapy treatment on the ovary highlighted that even within this field, there is a near complete absence of human data ( Spears et al. 2019 ). In this review, we will use
Dareen Mattar, Warakorn Cheewasopit, Moafaq Samir, and Phil G Knight
gonadotrophin (hCG) ( Laoharatchatathanin et al. 2015 ). To our knowledge, information is lacking on the extent to which kisspeptin and its receptor are expressed in the ovary and other endocrine tissues of cattle. In rats, kisspeptin and kisspeptin receptor
Synneva Hagen-Lillevik, John S Rushing, Leslie Appiah, Nicola Longo, Ashley Andrews, Kent Lai, and Joshua Johnson
reproductive years, there is a general lack of established ‘best practice’ strategies. These gaps also include open questions about the mechanism(s) by which galactosemic metabolic perturbations impact reproductive organs, in particular, the ovary. Indeed
Kate Anthony, Tyler Bruce Garner, Ramesh Ramachandran, and Francisco Javier Diaz
on RF according to the breeder’s guidelines. The RF group was closely monitored to assure recommended growth rate until ovary collection at 10 or 16 weeks. Feed was purchased from Wenger Feeds (Rheems, PA, USA), and the same starter, grower, and
Lauren R Alesi, Quynh-Nhu Nguyen, Jessica M Stringer, Amy L Winship, and Karla J Hutt
prioritised. Female fertility is governed by the quantity and quality of oocytes, which are stored in the ovary within primordial follicles. Cytotoxic chemotherapy, in addition to radiotherapy and surgery, has long been the mainstay of many cancer treatment
Briet D Bjarkadottir, Charlotte A Walker, Muhammad Fatum, Sheila Lane, and Suzannah A Williams
R Nevin L Anderson RA Spears N 2020 Single and combined effects of cisplatin and doxorubicin on the human and mouse ovary in vitro . Reproduction 159 193 – 204 . ( https://doi.org/10.1530/REP-19-0279 ) 31821159 McLaughlin M Innell
Kendall A Hyde, Francisco L N Aguiar, Benner G Alves, Kele A Alves, Gustavo D A Gastal, Melba O Gastal, and Eduardo L Gastal
Introduction At birth in most species, a finite pool of preantral follicles exists in the ovaries of females ( Kezele et al. 2002 ), which characterizes the main oocyte reserve of a given individual. Studies aiming to characterize the
