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Emmanuel Amabebe Academic Unit of Reproductive and Developmental Medicine, Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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Steven Reynolds Academic Unit of Radiology, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK

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Dilly O C Anumba Academic Unit of Reproductive and Developmental Medicine, Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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The connection between vaginal microbiota-metabolite profiles and preterm delivery (PTD, birth <37 weeks’ gestation) has been a topical subject. Previous research has focused on specific metabolites using proton NMR spectroscopy ( 1 H

Article Type:
Brief Report
DOI:
https://doi.org/10.1530/RAF-21-0065
Volume/Issue:
Volume 2: Issue 4
Open access
Yorain Sri Ranjan Human Development and Health, University of Southampton, Southampton, UK

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Nida Ziauddeen School of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, University of Southampton, Southampton, UK
NIHR Applied Research Collaboration Wessex, Southampton, UK

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Beth Stuart Centre for Evaluation and Methods, Wolfson Institute of Population Health, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK

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Nisreen A Alwan School of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, University of Southampton, Southampton, UK
NIHR Applied Research Collaboration Wessex, Southampton, UK
NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK

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Ying Cheong Human Development and Health, University of Southampton, Southampton, UK
Complete Fertility, Princess Anne Hospital, Southampton, UK

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increase the risk of birth-related complications, such as caesarean sections (CS), preterm delivery (PTD), placenta praevia (PP), and placental abruption (PA), and maternal medical disorders such as gestational diabetes (GDM) and hypertensive disorders of

Article Type:
Review Article
DOI:
https://doi.org/10.1530/RAF-22-0070
Volume/Issue:
Volume 4: Issue 1
Open access
Noble K Kurian Department of Microbiology, Atmiya University, Rajkot, Gujarat, India

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Deepak Modi Molecular and Cellular Biology Laboratory, ICMR-National Institute for Research in Reproductive Health and Child Health (NIRRCH), Indian Council of Medical Research (ICMR), Mumbai, India

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individual cases, it is difficult to assess whether the infection is the sole contributor to preterm delivery. However, several pieces of evidence ascertain that the infection and its resultant inflammation is the primary cause in a substantial proportion of

Article Type:
Review Article
DOI:
https://doi.org/10.1530/RAF-21-0105
Volume/Issue:
Volume 3: Issue 3
Open access
Emmanuel Amabebe Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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Noopur Bhatnagar Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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Nitin Kamble School of Dentistry, University of Sheffield, Sheffield, UK

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Steven Reynolds Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK

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Dilly O Anumba Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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/inflammation-associated preterm delivery within 14 days of presentation with symptoms of preterm labour: a multivariate predictive model . PLoS ONE 14 e0222455. ( https://doi.org/10.1371/journal.pone.0222455 ) Happel AU Kullin B Gamieldien H Wentzel N Zauchenberger

Article Type:
Letter
DOI:
https://doi.org/10.1530/RAF-22-0026
Volume/Issue:
Volume 3: Issue 3
Open access
Emmanuel Amabebe Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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Henry Ogidi Department of Obstetrics and Gynaecology, Glan Clwyd Hospital North Wales, Gwynedd, UK

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Dilly O Anumba Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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al. 2013 ). Role of matrix metalloproteinases in cervical remodelling associated with term and preterm delivery Activation of MMPs and collagen degradation are involved in the common pathway to cervical remodelling in both term and preterm

Article Type:
Review Article
DOI:
https://doi.org/10.1530/RAF-22-0015
Volume/Issue:
Volume 3: Issue 3
Open access