Intracytoplasmic sperm injection (ICSI) is highly effective for male factor infertility. However, its use for non-male factor infertility has increased dramatically worldwide in the last 2 decades despite little evidence demonstrating
Bhorika Aggarwal, Amanda L Evans, Howard Ryan, and Sarah J Martins da Silva
G Hughes and S Martins da Silva
impaired spermatogenesis prior to assisted conception reported 52% (34/66) risk of azoospermia in at least one ICSI attempt when at least one total sperm count was <100,000 vs 3% (5/181) when all counts were ≥100,000 ( P < 0.0001) ( Montagut et al. 2015
Madara S B Ralapanawe, Sugandika Lakmali Gajaweera, Nishendra Karunaratne, Malcolm James Price, Pedro Melo, Arri Coomarasamy, and Ioannis Gallos
Introduction Infertility is common, affecting one in eight couples worldwide ( ESHRE 2020 ). Assisted reproductive technology (ART), including in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI), is the mainstay
Rumiana Ganeva, Dimitar Parvanov, Denitsa Velikova, Magdalena Vasileva, Kristina Nikolova, and Georgi Stamenov
associated with low fertilization, implantation, and pregnancy rates ( Kruger et al. 1988 , Kahraman et al. 1999 , Osawa et al. 1999 ). Therefore embryologists tend to select morphologically normal spermatozoa for ICSI. Recently other sperm
I Robertson, F P Chmiel, and Y Cheong
model and simple tool to improve this prediction and facilitate communication. Methods Retrospective analysis developing and validating a machine-learning model using the HFEA 2015–2016 anonymised register ( HFEA 2018 ). In total, 86,169 IVF/ICSI
Mohamed Elkalyoubi, Larissa Schindler, and Hena Zaheer
sperm injection (ICSI) using their autologous oocytes. Methods Literature search One investigator conducted a systematic literature search of the PubMed, Google Scholar, and Cochrane library databases. The medical subject headings of growth
C C Repelaer van Driel-Delprat, E W C M van Dam, P M van de Ven, K Aissa, M K ter Haar, Y Feenstra, A de Roos, G Beelen, R Schats, and C B Lambalk
(IVF) or intracytoplasmatic sperm injection (ICSI) vary concerning associated live birth rate, clinical pregnancy, pregnancy loss, fertilization rate and embryo quality ( Zhong 2012 , Zhao et al. 2018 ). Overall, because of different study designs
Madeleine L H Campbell
, Rizzo et al. 2019 ). The harm associated with a procedure relates not only to the level of harm but also to the frequency with which that harm is applied. Oocyte retrieval as a precursor to IVF or ICSI often requires repeated cycles of hormonal
Pierre Comizzoli, Xiaoming He, and Pei-Chih Lee
injection (ICSI) as sperm cells are not motile after rehydration. Most common storage containers for lyophilized sperm cells are glass ampoules/vials ( Fig. 1 ). Recently, it has been demonstrated in mouse that freeze-drying on weighing paper and then
Parijot Kumar, Kevin Marron, and Conor Harrity
Headings (MeSH) and keywords were used to create subsets, including 'pregnancy' OR 'miscarriage' OR 'assisted reproduction' (ART) OR 'IVF' (in vitro fertilization) OR 'ICSI' (intra cytoplasmic sperm injections) OR 'implantation' OR 'Natural Killer' (NK
