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Maria Handzhiyska Department of Research, Nadezhda Women’s Health Hospital, Sofia, Bulgaria

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Rumiana Ganeva Department of Research, Nadezhda Women’s Health Hospital, Sofia, Bulgaria

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Dimitar Parvanov Department of Research, Nadezhda Women’s Health Hospital, Sofia, Bulgaria

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Margarita Ruseva Department of Research, Nadezhda Women’s Health Hospital, Sofia, Bulgaria

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Petar Eftimov Department of Cell and Developmental Biology, Faculty of Biology, SU St. Climent Ohridski, Sofia, Bulgaria

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Vilyana Georgieva Department of Andrology, Nadezhda Women’s Health Hospital, Sofia, Bulgaria

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Denitsa Velikova Department of Andrology, Nadezhda Women’s Health Hospital, Sofia, Bulgaria

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Georgi Stamenov Department of Obstetrics and Gynecology, Nadezhda Women’s Health Hospital, Sofia, Bulgaria

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-mediated sperm binding ( Huszar et al. 2007 , West et al. 2022 ) and magnetic-activated cell sorting ( Nadalini et al. 2014 ). Another innovative sperm selection technique involving cumulus matrix (CM) penetration in a dish has recently been developed

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-23-0052
Volume/Issue:
Volume 5: Issue 2
Open access
R Appeltant Nuffield Department of Women’s and Reproductive Health, Women’s Centre, John Radcliffe Hospital, University of Oxford, Oxford, UK

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B V Adeniran Nuffield Department of Women’s and Reproductive Health, Women’s Centre, John Radcliffe Hospital, University of Oxford, Oxford, UK

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S A Williams Nuffield Department of Women’s and Reproductive Health, Women’s Centre, John Radcliffe Hospital, University of Oxford, Oxford, UK

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cumulus matrix, which plays a key role in in vivo fertilization ( Salustri et al . 2004 ). In the ovary, HA is to be found not only in the cumulus matrix ( Lo et al . 2019 ) but also in the theca cells and follicular fluid ( Christensen et al . 2015

Article Type:
Brief Report
DOI:
https://doi.org/10.1530/RAF-21-0085
Volume/Issue:
Volume 2: Issue 4
Open access
Heidy Kaune Laboratory of Reproduction, Centre for Biomedical Research, Faculty of Medicine, Universidad Diego Portales, Santiago, Chile
Program of Ethics and Public Policies in Human Reproduction, Universidad Diego Portales, Santiago, Chile

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Juan F Montiel Laboratory of Integrative Neuroscience, Centre for Biomedical Research, Faculty of Medicine, Universidad Diego Portales, Santiago, Chile

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Mark Fenwick Academic Unit of Reproductive and Developmental Medicine, University of Sheffield, Sheffield, UK

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Suzannah A Williams Nuffield Department of Women’s and Reproductive Health, Women’s Centre, John Radcliffe Hospital, University of Oxford, Oxford, UK

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210 genes grouped in this cluster and a high enrichment score of 5.95. The following clusters are extracellular matrix, immune response, LPA (lipoprotein, propeptides, and anchored to the membrane), and cell adhesion. Table 2 Top five functional

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-22-0036
Volume/Issue:
Volume 3: Issue 3
Open access
Iman Al-Saleh Environmental Health Program, Research Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Serdar Coskun Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Reem Al-Rouqi Environmental Health Program, Research Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Tahreer Al-Rajudi Environmental Health Program, Research Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Chafica Eltabache Environmental Health Program, Research Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Mai Abduljabbar Environmental Health Program, Research Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Saad Al-Hassan Reproductive Medicine Unit, Department of Obstetrics and Gynecology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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2001 Cumulus oophorus extracellular matrix: its construction and regulation . Cell Structure and Function 26 189 – 196 . ( https://doi.org/10.1247/csf.26.189 ) Zubair M Ahmad M Qureshi ZI 2017 Review on arsenic-induced toxicity in male

Article Type:
Research Article
Collections:
Clinical research and reviews
DOI:
https://doi.org/10.1530/RAF-20-0062
Volume/Issue:
Volume 2: Issue 2
Open access
Perihan Sezginer Department of Medical Laboratory Techniques, Alanya Alaaddin Keykubat University, Health Services Vocational School, Alanya, Turkey

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Cigdem Elmas Department of Histology and Embryology, Gazi University, Faculty of Medicine, Ankara, Turkey

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Fatma Yıldız Department of Medical Laboratory Techniques, Alanya Alaaddin Keykubat University, Health Services Vocational School, Alanya, Turkey

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Discussion Some extracellular matrix components and growth factors that act in an autocrine-paracrine manner play role in the growth process of the ovarian follicles, which are the functional units of ovaries ( Eppig 2001 , Skinner 2005 , Li et al . 2010

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-21-0075
Volume/Issue:
Volume 3: Issue 3
Open access
Jennifer B Nagashima Center for Species Survival, Smithsonian Conservation Biology Institute, National Zoological Park, Front Royal, Virginia, USA

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Andrea M Hill Center for Species Survival, Smithsonian Conservation Biology Institute, National Zoological Park, Front Royal, Virginia, USA

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Nucharin Songsasen Center for Species Survival, Smithsonian Conservation Biology Institute, National Zoological Park, Front Royal, Virginia, USA

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.4L). The Liberase TM enzyme blend contains the neutral protease thermolysin, which disrupts the extracellular matrix of the tissue and it has been shown to maintain normal morphology in isolated ovarian follicles better than collagenase ( Dolmans et

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-20-0067
Volume/Issue:
Volume 2: Issue 1
Open access
Rolando Pasquariello Colorado Center for Reproductive Medicine, Lone Tree, Colorado, USA
Colorado State University, Fort Collins, Colorado, USA

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Mingxiang Zhang Colorado Center for Reproductive Medicine, Lone Tree, Colorado, USA

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Jason R Herrick Colorado Center for Reproductive Medicine, Lone Tree, Colorado, USA
Omaha’s Henry Doorly Zoo and Aquarium, Omaha, Nebraska, USA

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Alison F Ermisch Colorado Center for Reproductive Medicine, Lone Tree, Colorado, USA

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John Becker Colorado Center for Reproductive Medicine, Lone Tree, Colorado, USA

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William B Schoolcraft Colorado Center for Reproductive Medicine, Lone Tree, Colorado, USA

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Jennifer P Barfield Colorado State University, Fort Collins, Colorado, USA

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Ye Yuan Colorado Center for Reproductive Medicine, Lone Tree, Colorado, USA

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Rebecca L Krisher Colorado Center for Reproductive Medicine, Lone Tree, Colorado, USA
Omaha’s Henry Doorly Zoo and Aquarium, Omaha, Nebraska, USA

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derivatized as described earlier. Oocyte in vitro maturation Ovaries were collected at an abattoir by a commercial supplier (BPO Parts LLC, CO, USA) and transported to the laboratory in warmed 0.9% saline. Bovine cumulus–oocyte complexes (COC) were

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-23-0057
Volume/Issue:
Volume 4: Issue 4
Open access
Menghe Liu School of Biomedicine, Robinson Research Institute, The University of Adelaide, Adelaide, SA, Australia

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Katja Hummitzsch School of Biomedicine, Robinson Research Institute, The University of Adelaide, Adelaide, SA, Australia

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Nicole A Bastian School of Biomedicine, Robinson Research Institute, The University of Adelaide, Adelaide, SA, Australia

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Monica D Hartanti School of Biomedicine, Robinson Research Institute, The University of Adelaide, Adelaide, SA, Australia
Faculty of Medicine, Universitas Trisakti, Jakarta, Indonesia
National Research and Innovation Agency, Jakarta, Indonesia

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Helen F Irving-Rodgers School of Biomedicine, Robinson Research Institute, The University of Adelaide, Adelaide, SA, Australia
School of Medical Science, Griffith University, Gold Coast Campus, QLD, Australia

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Richard A Anderson MRC Centre for Reproductive Health, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK

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Raymond J Rodgers School of Biomedicine, Robinson Research Institute, The University of Adelaide, Adelaide, SA, Australia

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deposition of extracellular matrix such as collagen type I ( Zhou et al. 2017 ). In terms of the origin of different cell types in the fetal ovary, fibroblasts are derived from the mesonephric stroma which penetrates from the mesonephros into the ovarian

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-22-0068
Volume/Issue:
Volume 3: Issue 4
Open access
Maria Dri Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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Francesca Gioia Klinger Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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Massimo De Felici Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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on the KITL mRNA transcription in cumulus cells likely mediated by GDF9 (growth differentiation factor 9) has been reported ( Joyce et al. 2000 ), although another oocyte-secreted factor BMP15 (bone morphogenetic factor 15) has been shown to

Article Type:
Review Article
DOI:
https://doi.org/10.1530/RAF-21-0038
Volume/Issue:
Volume 2: Issue 3
Open access