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Pierre Comizzoli Smithsonian Conservation Biology Institute, National Zoological Park, Washington, District of Columbia, USA

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Xiaoming He Fischell Department of Bioengineering, University of Maryland, College Park, Maryland, USA

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Pei-Chih Lee Smithsonian Conservation Biology Institute, National Zoological Park, Washington, District of Columbia, USA

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is a specific interest in preserving spermatozoa, eggs, embryos, and gonadal tissues (so-called germplasms) in human reproductive medicine, livestock production, laboratory animal management, and wild species conservation ( Saragusty et al. 2020

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Talita De Oliveira Farias Laboratory of Cellular Biology, Department of Morphology, Federal University of Minas Gerais - UFMG, Belo Horizonte, MG, Brazil

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André Felipe Almeida Figueiredo Laboratory of Cellular Biology, Department of Morphology, Federal University of Minas Gerais - UFMG, Belo Horizonte, MG, Brazil

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Natalia Teixeira Wnuk Laboratory of Cellular Biology, Department of Morphology, Federal University of Minas Gerais - UFMG, Belo Horizonte, MG, Brazil

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Sônia Aparecida Talamoni Laboratory of Mastozoology, Department of Biological Sciences, Pontifical Catholic University of Minas Gerais - PUC Minas, Belo Horizonte, MG, Brazil

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Guilherme Mattos Jardim Costa Laboratory of Cellular Biology, Department of Morphology, Federal University of Minas Gerais - UFMG, Belo Horizonte, MG, Brazil

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studies of seasonal species because the gonads are transferred to a more stable endocrine milieu. Another interesting observation is that the brown adipose tissue (B.A.T.) mass varies in the same pattern as the accessory sex gland mass throughout the

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Dareen Mattar Department of Physiology, College of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia

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Warakorn Cheewasopit Department of Biology, Ramkhamhaeng University, Bankapi, Bangkok, Thailand

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Moafaq Samir The Ministry of Higher Education and Scientific Research, Baghdad, Iraq

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Phil G Knight School of Biological Sciences, University of Reading, Whiteknights, Reading, UK

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primarily at the hypothalamic level to regulate GnRH output, there is mounting evidence that kisspeptin and/or its receptor are expressed at other levels of the reproductive system, including the gonads ( Gaytan et al. 2009 , Naniwa et al. 2013

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Peter H Vogt Division of Reproduction Genetics, Department of, Gynaecol. Endocrinology & Infertility Disorders, Women Hospital, University of Heidelberg, Germany

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Jutta Zimmer Division of Reproduction Genetics, Department of, Gynaecol. Endocrinology & Infertility Disorders, Women Hospital, University of Heidelberg, Germany

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Ulrike Bender Division of Reproduction Genetics, Department of, Gynaecol. Endocrinology & Infertility Disorders, Women Hospital, University of Heidelberg, Germany

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Thomas Strowitzki Department of Gynaecol. Endocrinology & Infertility Disorders, Women Hospital, University of Heidelberg, Germany

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indicated in the figure legends; and of the University of Heidelberg and of Bonn for the adult samples (4× KOHO3 specimens always used as the control sample for testis sections; 2× ovarian tissue sections from sample #1469/99; 4× DSD-46,XY: 2× gonadal tissue

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Rod T Mitchell MRC Centre for Reproductive Health, The Queen’s Medical Research Institute, The University of Edinburgh, Edinburgh, UK
Department of Paediatric Endocrinology, Royal Hospital for Children and Young People, Edinburgh, UK

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Suzannah A Williams Nuffield Department of Women’s and Reproductive Health, Women’s Centre, John Radcliffe Hospital, University of Oxford, Oxford, UK

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describing the current progress and future of ARTs in preserving endangered species. The use of biobanking by cryopreservation of germ cells, gonads and tissues from both males and females to prevent the loss of endangered species is also key to retaining

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Jennifer Dabel Institute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Muenster, Germany

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Florian Schneider Institute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Muenster, Germany
Department of Clinical Andrology, Centre of Reproductive Medicine and Andrology, Muenster, Germany

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Joachim Wistuba Institute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Muenster, Germany

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Sabine Kliesch Department of Clinical Andrology, Centre of Reproductive Medicine and Andrology, Muenster, Germany

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Stefan Schlatt Institute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Muenster, Germany

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Nina Neuhaus Institute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Muenster, Germany

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testicular tissues into the scrotum and in vitro spermatogenesis ( Medrano et al. 2018 , Sharma et al. 2019 ). As the former two approaches require male gonads to achieve spermatogenesis, in particular, the approach of in vitro spermatogenesis may

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Charvi Kanodia Edinburgh Medical School, University of Edinburgh, UK

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Michael P Rimmer MRC Centre for Reproductive Health, Institute of Regeneration and Repair, University of Edinburgh, UK

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Kathleen Duffin Biomedical Sciences, University of Edinburgh, UK

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Rod T Mitchell MRC Centre for Reproductive Health, Institute of Regeneration and Repair, University of Edinburgh, UK

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has ever been born from cryopreserved pre-pubertal testis tissue, with the most recent breakthrough in this area being the birth of a Rhesus Macaque following autologous transplant of cryopreserved pre-pubertal testis tissue ( Fayomi et al. 2019

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W G Foster Department of Obstetrics & Gynecology, McMaster University, Hamilton, Ontario, Canada

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M Leonardi Department of Obstetrics & Gynecology, McMaster University, Hamilton, Ontario, Canada

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variable and dependent on the tissue on which it grows. Hallmark features of endometriosis include pelvic pain and infertility; however, some people with endometriosis remain asymptomatic. Endometriosis is a disease whose impact on the health care system

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Awang Hazmi Awang-Junaidi Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

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Mohammad Amin Fayaz Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

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Savannah Goldstein Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

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Ali Honaramooz Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

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folding of different germinal layers and extensive migration of both germ cells and somatic cells must result in the compartmentalization of the tissue into testicular cords and an inter-tubular interstitium ( Lamb 1993 ). Testicular/seminiferous cords (SC

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Christina M Merkley Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA

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Allison N Renwick Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA

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Sydney L Shuping Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA

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KaLynn Harlow Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA

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Jeffrey R Sommer Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA

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Casey C Nestor Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA

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Introduction The capacity for reproduction first occurs at puberty and is the result of an activated hypothalamic–pituitary–gonadal axis. As a critical window of time in physiological development, puberty onset is heralded at the

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