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Mary Ann Ottinger Department of Biology and Biochemistry, University of Houston, Houston, Texas, USA

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Shailaja Mani Department of Molecular & Cellular Biology and Neuroscience, Baylor College of Medicine, Houston, Texas, USA

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Sonja Krüger Ezemvelo KwaZulu-Natal Wildlife, Scientific Services, Queen Elizabeth Park, 1 Peter Brown Drive, Pietermaritzburg, South Africa
Centre for Functional Biodiversity, School of Life Sciences, University of KwaZulu-Natal, Pietermaritzburg, South Africa

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Brent Coverdale Ezemvelo KwaZulu-Natal Wildlife, Scientific Services, Queen Elizabeth Park, 1 Peter Brown Drive, Pietermaritzburg, South Africa

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Sandi Willows-Munro Centre for Functional Biodiversity, School of Life Sciences, University of KwaZulu-Natal, Pietermaritzburg, South Africa

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Leigh Combrink School of Natural Resources and the Environment, University of Arizona, Tucson, Arizona, USA

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integrating factors exert increasing stress, leading to diminished metabolic, immune, and reproductive functions, contributing to deteriorating overall health and reduced longevity ( Ottinger & Geiselman 2023 ). This drastic loss of avian species underscores

Article Type:
Review Article
DOI:
https://doi.org/10.1530/RAF-23-0076
Volume/Issue:
Volume 5: Issue 3
Open access
Caitriona Brennan Department of Pediatrics, University of California San Diego, La Jolla, California, USA
Division of Biological Sciences, University of California San Diego, La Jolla, California, USA

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Kristina Chan Department of Pediatrics, University of California San Diego, La Jolla, California, USA
Department of Bioengineering, University of California, San Diego, La Jolla, California, USA

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Tanya Kumar Medical Scientist Training Program, University of California San Diego, La Jolla, California, USA

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Erica Maissy Division of Gastroenterology, University of California San Diego, La Jolla, California, USA
Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, California, USA

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Linda Brubaker Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, La Jolla, California, USA

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Marisol I Dothard Department of Pediatrics, University of California San Diego, La Jolla, California, USA
Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, California, USA

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Jack A Gilbert Department of Pediatrics, University of California San Diego, La Jolla, California, USA
Center for Microbiome Innovation, University of California San Diego, La Jolla, California, USA

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Katharine E Gilbert Department of Pediatrics, University of California San Diego, La Jolla, California, USA

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Amanda L Lewis Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, La Jolla, California, USA

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Varykina G Thackray Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, La Jolla, California, USA
Center for Microbiome Innovation, University of California San Diego, La Jolla, California, USA

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Amir Zarrinpar Department of Bioengineering, University of California, San Diego, La Jolla, California, USA
Medical Scientist Training Program, University of California San Diego, La Jolla, California, USA
Division of Gastroenterology, University of California San Diego, La Jolla, California, USA
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, La Jolla, California, USA
Center for Microbiome Innovation, University of California San Diego, La Jolla, California, USA
Jennifer Moreno Department of Veterans Affairs Medical Center, La Jolla, California, USA
Institute of Diabetes and Metabolic Health, University of California San Diego, La Jolla, California, USA

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Rob Knight Department of Pediatrics, University of California San Diego, La Jolla, California, USA
Department of Bioengineering, University of California, San Diego, La Jolla, California, USA
Center for Microbiome Innovation, University of California San Diego, La Jolla, California, USA
Department of Computer Science and Engineering, University of California, San Diego, La Jolla, California, USA
Halıcıoğlu Data Science Institute, University of California San Diego, La Jolla, California, USA

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Introduction The human microbiome comprises trillions of bacteria, archaea, fungi, protists, and viruses that play crucial roles in maintaining health and influencing progression of disease. There is considerable variation in the microbial

Article Type:
Review Article
DOI:
https://doi.org/10.1530/RAF-23-0060
Volume/Issue:
Volume 5: Issue 2
Open access
Tarimoboere Agbalalah Department of Anatomy, Faculty of Basic Medical Sciences, Baze University, Abuja, Nigeria
Department of Medical Biotechnology, National Biotechnology Development Agency, Abuja, Nigeria

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Faith Owabhel Robert Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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Emmanuel Amabebe Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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, particularly those with limited access to comprehensive team care and the high cost of care. SCD is a global public health burden. It is highly prevalent in malaria-endemic regions and commonly encountered in Africans, Mediterraneans and South Asians. Africa

Article Type:
Review Article
DOI:
https://doi.org/10.1530/RAF-23-0015
Volume/Issue:
Volume 4: Issue 3
Open access
Jack Wilkinson Centre for Biostatistics, Division of Population Health, Health Services Research and Primary Care, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, UK

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Katie Stocking Centre for Biostatistics, Division of Population Health, Health Services Research and Primary Care, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, UK

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, success of the embryo transfer, the outcome of pregnancy and health of any resulting offspring can all be measured and reported in a study involving in vitro fertilisation (IVF) ( Heijnen et al. 2004 ). Accordingly, a recent review of outcome reporting

Article Type:
Discussion
DOI:
https://doi.org/10.1530/RAF-21-0015
Volume/Issue:
Volume 2: Issue 2
Open access
Emily Bailie Institute of Cell Biology, Hugh Robson Building, University of Edinburgh, Edinburgh, UK

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Mila Maidarti Institute of Cell Biology, Hugh Robson Building, University of Edinburgh, Edinburgh, UK

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Robert Hawthorn Queen Elizabeth University Hospital, Glasgow, UK

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Stuart Jack Simpson Centre for Reproductive Health, Royal Infirmary, Edinburgh, UK

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Neale Watson Spire Thames Valley Hospital, Wexham St, Slough, UK

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Evelyn E Telfer Institute of Cell Biology, Hugh Robson Building, University of Edinburgh, Edinburgh, UK

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Richard A Anderson MRC Centre for Reproductive Health, Queens Medical Research Institute, University of Edinburgh, Edinburgh, UK

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function and follicle health ( Bertoldo et al. 2019 ). Excessive androgen as demonstrated in the ovaries of females with polycystic ovary syndrome (PCOS) results in an increase in follicular recruitment with subsequent arrest in follicle development and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-22-0102
Volume/Issue:
Volume 4: Issue 2
Open access
Evangeline R Walker Department of Reproductive Medicine, Old Saint Mary’s Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK

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Mollie McGrane Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
Maternal and Fetal Health Research Centre, Saint Mary’s Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK

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John D Aplin Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
Maternal and Fetal Health Research Centre, Saint Mary’s Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK

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Daniel R Brison Department of Reproductive Medicine, Old Saint Mary’s Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK
Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
Maternal and Fetal Health Research Centre, Saint Mary’s Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK

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Peter T Ruane Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
Maternal and Fetal Health Research Centre, Saint Mary’s Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK

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withdrawal in the menses phase ( Aplin et al. 2008 ). Biologists, gynaecologists and obstetricians have long sought to understand the menstrual cycle to improve women’s and children’s health ( Critchley et al. 2020 ), and the interest in characterising

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-22-0115
Volume/Issue:
Volume 4: Issue 3
Open access
Michelle Engelsman Fire and Rescue NSW, Greenacre, New South Wales, Australia
QAEHS, Queensland Alliance for Environmental Health Sciences, The University of Queensland, Woolloongabba, Queensland, Australia

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Leisa-Maree L Toms School of Public Health and Social Work, Faculty of Health, Queensland University of Technology, Kelvin Grove, Australia

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Xianyu Wang QAEHS, Queensland Alliance for Environmental Health Sciences, The University of Queensland, Woolloongabba, Queensland, Australia

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Andrew P W Banks QAEHS, Queensland Alliance for Environmental Health Sciences, The University of Queensland, Woolloongabba, Queensland, Australia

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Debbie Blake Repromed, Remuera, Auckland, New Zealand

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The University of Queensland, 20 firefighters contributed 23 semen samples at specified pathology centres. Semen samples were analysed in line with the World Health Organisation (WHO) methodology. Not all samples were analysed within 60 min due to

Article Type:
Brief Report
DOI:
https://doi.org/10.1530/RAF-20-0070
Volume/Issue:
Volume 2: Issue 1
Open access
W Colin Duncan MRC Centre for Reproductive Health, The University of Edinburgh, Queen’s Medical Research Institute, Edinburgh, UK

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biologically plausible potential impact of maternal therapeutic progesterone supplementation and a longer-term impact on offspring health, not evident at birth. It, therefore, seems sensible to limit pharmaceutical progesterone exposure in early pregnancy to

Article Type:
Article Commentary
DOI:
https://doi.org/10.1530/RAF-21-0122
Volume/Issue:
Volume 3: Issue 2
Open access
Cecilia H M Ng School of Clinical Medicine, Division of Obstetrics and Gynaecology, Health and Medicine, UNSW, Sydney, New South Wales, Australia
Jean Hailes for Women’s Health, Melbourne, Victoria, Australia

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Andrew G Michelmore Jean Hailes for Women’s Health, Melbourne, Victoria, Australia

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Gita D Mishra School of Public Health, University of Queensland, Herston, Queensland, Australia

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Grant W Montgomery Institute of Molecular Bioscience, University of Queensland, St Lucia, Queensland, Australia

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Peter A Rogers Jean Hailes for Women’s Health, Melbourne, Victoria, Australia
Department of Obstetrics and Gynaecology, Royal Women’s Hospital, University of Melbourne, Parkville, Victoria, Australia

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Jason A Abbott School of Clinical Medicine, Division of Obstetrics and Gynaecology, Health and Medicine, UNSW, Sydney, New South Wales, Australia
Gynaecological Research and Clinical Evaluation (GRACE) Unit, Royal Hospital for Women, Randwick New South Wales, Australia

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/or associated conditions (e.g. adenomyosis). This clinical and health information from the registry is capturing patient-reported outcomes for endometriosis and how endometriosis affects people’s lives and is identifying trends in clinical management and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-23-0014
Volume/Issue:
Volume 4: Issue 2
Open access
Soo Young Baik Discovery and Translational Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom

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Alisha Maini Discovery and Translational Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom

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Haidee Tinning Discovery and Translational Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom

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Dapeng Wang LeedsOmics, University of Leeds, Leeds, United Kingdom
Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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Daman J Adlam Faculty of Biology, Medicine and Health, Division of Developmental Biology and Medicine, Maternal and Fetal Health Research Centre, School of Medical Sciences, Saint Mary’s Hospital, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK
Maternal and Fetal Health Research Centre, Saint Mary’s Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, UK

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Peter T Ruane Faculty of Biology, Medicine and Health, Division of Developmental Biology and Medicine, Maternal and Fetal Health Research Centre, School of Medical Sciences, Saint Mary’s Hospital, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK
Maternal and Fetal Health Research Centre, Saint Mary’s Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, UK

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Niamh Forde Discovery and Translational Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom

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profile of those suffering from obesity, there are resulting complex health issues including insulin resistance and compensatory hyperinsulinaemia ( Talmor & Dunphy 2015 ). This has been linked to poor reproductive outcomes in women of childbearing age

Article Type:
Research Article
DOI:
https://doi.org/10.1530/RAF-21-0120
Volume/Issue:
Volume 4: Issue 2
Open access