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Gynecologic Division, BP – A Beneficencia Portuguesa de Sao Paulo, Sao Paulo, Sao Paulo, Brazil
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Gynecologic Division, BP – A Beneficencia Portuguesa de Sao Paulo, Sao Paulo, Sao Paulo, Brazil
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endometriosis 36.1 ± 5.6 Cervical canal (67), posterior fornix (65), eutopic endometrium (2) Microbiome Shotgun sequencing 36 controls: infertility, myomas, ovarian borderline tumor, and teratoma Hernandes et al. (2020) Case
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and/or infertility whether pathology is identified or not. Argument 1: diagnostic laparoscopy is safe Overall, laparoscopy is a low-risk procedure. A Cochrane review of entry techniques which included 57 studies and 9865 participants noted that
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Background Endometriosis affects 10% of women of reproductive age and nearly 90% of women with chronic pelvic pain and infertility ( Lorusso et al. 2021 ). It is defined as the presence of endometrial-like tissue outside the uterus. The most
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infertility ( Meuleman et al. 2009 ): rates in adolescents with pelvic pain range from 49% to 75% ( Shafrir et al. 2018 ). A recent review highlighted the profound negative impact on the lives of individuals with the disorder ( Missmer et al. 2021
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McMaster University Health Sciences Center, Hamilton, Ontario, Canada
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most commonly affects individuals from menarche through menopause, though it can also affect adolescents and postmenopausal women. It is a common cause of pain and infertility but also negatively impacts quality of life, intimate relationships
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endometrial glands and stroma and may present with a variety of symptoms such as pelvic pain and infertility, resulting in a significant negative impact on individuals’ health and quality of life ( Nnoaham et al. 2011 , Zondervan et al. 2018 , Missmer
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variable and dependent on the tissue on which it grows. Hallmark features of endometriosis include pelvic pain and infertility; however, some people with endometriosis remain asymptomatic. Endometriosis is a disease whose impact on the health care system
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Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
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, painful intercourse, and infertility; however, non-specific symptoms often accompany these more prominent features. Treatments in the domains of medical management, surgery, and alternative management can be effective for many if used optimally but may not
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Departamento de Ginecologia, Universidade Federal de São Paulo, São Paulo, Brazil
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Biobehavioral Pediatric Pain Lab, Department of Psychiatry, Boston Children’s Hospital, Boston, Massachusetts, USA
Pain and Affective Neuroscience Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children’s Hospital, Massachusetts, USA
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Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK
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, Facchin et al. 2017 , Zondervan et al. 2018 ). The symptoms of infertility and dyspareunia add to the psychological burden of people suffering with endometriosis and increase the levels of perceived stress while also negatively affecting the patients
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long-chain omega 3 fatty acids ( Missmer et al. 2010 ) were associated with a lower risk of developing endometriosis. In a population of infertile women, an association was found between intake of caffeinated beverages and endometriosis ( Grodstein
