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Emmanuel Amabebe Academic Unit of Reproductive and Developmental Medicine, Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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Steven Reynolds Academic Unit of Radiology, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK

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Dilly O C Anumba Academic Unit of Reproductive and Developmental Medicine, Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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these groups by metabolite profile alone – only CST-I appeared to be separated. Although the vaginal microbiota may increasingly be dominated by lactobacilli during pregnancy, the risk of infection-inflammation-associated spontaneous PTD may still be

Article Type:
Brief Report
DOI:
https://doi.org/10.1530/RAF-21-0065
Volume/Issue:
Volume 2: Issue 4
Open access
Emmanuel Amabebe Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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Noopur Bhatnagar Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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Nitin Kamble School of Dentistry, University of Sheffield, Sheffield, UK

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Steven Reynolds Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK

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Dilly O Anumba Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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lactobacilli. Three different preparations of L. crispatus : bacterial suspension in De Man, Rogosa and Sharpe media, centrifuged not filtered (supernatant with fewer cells), and filtered supernatant from centrifuged sample (cell-free supernatant) were co

Article Type:
Letter
DOI:
https://doi.org/10.1530/RAF-22-0026
Volume/Issue:
Volume 3: Issue 3
Open access
Caitriona Brennan Department of Pediatrics, University of California San Diego, La Jolla, California, USA
Division of Biological Sciences, University of California San Diego, La Jolla, California, USA

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Kristina Chan Department of Pediatrics, University of California San Diego, La Jolla, California, USA
Department of Bioengineering, University of California, San Diego, La Jolla, California, USA

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Tanya Kumar Medical Scientist Training Program, University of California San Diego, La Jolla, California, USA

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Erica Maissy Division of Gastroenterology, University of California San Diego, La Jolla, California, USA
Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, California, USA

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Linda Brubaker Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, La Jolla, California, USA

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Marisol I Dothard Department of Pediatrics, University of California San Diego, La Jolla, California, USA
Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, California, USA

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Jack A Gilbert Department of Pediatrics, University of California San Diego, La Jolla, California, USA
Center for Microbiome Innovation, University of California San Diego, La Jolla, California, USA

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Katharine E Gilbert Department of Pediatrics, University of California San Diego, La Jolla, California, USA

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Amanda L Lewis Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, La Jolla, California, USA

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Varykina G Thackray Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, La Jolla, California, USA
Center for Microbiome Innovation, University of California San Diego, La Jolla, California, USA

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Amir Zarrinpar Department of Bioengineering, University of California, San Diego, La Jolla, California, USA
Medical Scientist Training Program, University of California San Diego, La Jolla, California, USA
Division of Gastroenterology, University of California San Diego, La Jolla, California, USA
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, La Jolla, California, USA
Center for Microbiome Innovation, University of California San Diego, La Jolla, California, USA
Jennifer Moreno Department of Veterans Affairs Medical Center, La Jolla, California, USA
Institute of Diabetes and Metabolic Health, University of California San Diego, La Jolla, California, USA

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Rob Knight Department of Pediatrics, University of California San Diego, La Jolla, California, USA
Department of Bioengineering, University of California, San Diego, La Jolla, California, USA
Center for Microbiome Innovation, University of California San Diego, La Jolla, California, USA
Department of Computer Science and Engineering, University of California, San Diego, La Jolla, California, USA
Halıcıoğlu Data Science Institute, University of California San Diego, La Jolla, California, USA

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-based disease arising from vaginal dysbiosis classically associated with fewer Lactobacilli present in the vagina and an increase in anaerobes, such as Gardnerella vaginalis , Fannyhessea (previously Atopobium ) vaginae , and Mycoplasma genitalium (a few

Article Type:
Review Article
DOI:
https://doi.org/10.1530/RAF-23-0060
Volume/Issue:
Volume 5: Issue 2
Open access
Emmanuel Amabebe Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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Henry Ogidi Department of Obstetrics and Gynaecology, Glan Clwyd Hospital North Wales, Gwynedd, UK

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Dilly O Anumba Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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in altering MMP activity for both labour and CIN/cancer The normal vaginal microbiota is dominated by lactobacilli and exhibits low immunostimulatory capacity in pregnant and non-pregnant state ( Amabebe & Anumba 2018 , 2020 ). An altered vaginal

Article Type:
Review Article
DOI:
https://doi.org/10.1530/RAF-22-0015
Volume/Issue:
Volume 3: Issue 3
Open access
Emmanuel Amabebe Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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Dilly O Anumba Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK

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, Tester & Al-Ghazzewi 2018 ). In addition to the lactic acid, the lactobacilli produce hydrogen peroxide and bacteriocins that inhibit the growth of BV-associated pathogens ( Amabebe & Anumba 2018 , Tester & Al-Ghazzewi 2018 ), thereby preventing

Article Type:
Review Article
Collections:
Clinical research and reviews
DOI:
https://doi.org/10.1530/RAF-20-0034
Volume/Issue:
Volume 2: Issue 1
Open access
Carlos H Miyashira Centro de Ensaios Clinicos, Fundação Butantan, São Paulo, Sao Paulo, Brazil

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Fernanda Reali Oliveira Departamento de Obstetricia e Ginecologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil

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Marina Paula Andres Departamento de Obstetricia e Ginecologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil
Gynecologic Division, BP – A Beneficencia Portuguesa de Sao Paulo, Sao Paulo, Sao Paulo, Brazil

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Julian A Gingold OB/GYN and Women’s Health, Division of Reproductive Endocrinology and Infertility, Montefiore Medical Center, Bronx, New York, USA

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Mauricio Simões Abrão Departamento de Obstetricia e Ginecologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil
Gynecologic Division, BP – A Beneficencia Portuguesa de Sao Paulo, Sao Paulo, Sao Paulo, Brazil

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cervical microbiota was similar between the two groups. Lactobacilli species were predominant in both groups whereas Enterobacteriaceae and Streptococcus were more prevalent in women with endometriosis ( P < 0.05). Chen et al. (2020) compared

Article Type:
Review Article
Collections:
Endometriosis
DOI:
https://doi.org/10.1530/RAF-21-0113
Volume/Issue:
Volume 3: Issue 3
Open access
S M O’Mahony Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland
APC Microbiome Ireland, University College Cork, Cork, Ireland

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P Comizzoli Smithsonian’s National Zoo and Conservation Biology Institute, Washington, District of Columbia, USA

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health. For example, females from many animal species, including humans, display a dominance of Lactobacillus spp. in their reproductive tract ( Chen et al. 2021 ). Lactobacilli have several beneficial properties including contributing to an acidic

Article Type:
Introduction
DOI:
https://doi.org/10.1530/RAF-23-0080
Volume/Issue:
Volume 4: Issue 4
Open access
Kei Odawara Obstetrics and Gynecology in the Department of Surgery, Showa University, Shinagawa-ku, Tokyo, Japan
Obstetrics and Gynecology, Showa University, Shinagawa-ku, Tokyo, Japan
Fertility Clinic Tokyo, Shibuya-ku, Tokyo, Japan

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Ryosuke Akino Obstetrics and Gynecology in the Department of Surgery, Showa University, Shinagawa-ku, Tokyo, Japan

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Akihiko Sekizawa Obstetrics and Gynecology in the Department of Surgery, Showa University, Shinagawa-ku, Tokyo, Japan

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Miwa Sakamoto Obstetrics and Gynecology, Showa University, Shinagawa-ku, Tokyo, Japan

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Seo Yuriko Fertility Clinic Tokyo, Shibuya-ku, Tokyo, Japan

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Kanako Tanaka Fertility Clinic Tokyo, Shibuya-ku, Tokyo, Japan

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Mutsumi Mikashima Fertility Clinic Tokyo, Shibuya-ku, Tokyo, Japan

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Masami Suzuki Fertility Clinic Tokyo, Shibuya-ku, Tokyo, Japan

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Yasushi Odawara Fertility Clinic Tokyo, Shibuya-ku, Tokyo, Japan

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effect on implantation success or failure . American Journal of Obstetrics and Gynecology 215 684 – 703 . ( https://doi.org/10.1016/j.ajog.2016.09.075 ) Skarin A Sylwan J 1986 Vaginal lactobacilli inhibiting growth of Gardnerella vaginalis

Article Type:
Research Article
Collections:
Clinical research and reviews
DOI:
https://doi.org/10.1530/RAF-20-0030
Volume/Issue:
Volume 2: Issue 1
Open access
Noble K Kurian Department of Microbiology, Atmiya University, Rajkot, Gujarat, India

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Deepak Modi Molecular and Cellular Biology Laboratory, ICMR-National Institute for Research in Reproductive Health and Child Health (NIRRCH), Indian Council of Medical Research (ICMR), Mumbai, India

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, it was reported that changes in healthy populations of lactobacilli in the vagina to a mixed-species microbiota predominated by Gardnerella vaginalis , Atopobium vaginae, and Prevotella sp. are associated with preterm births ( Crosby et al

Article Type:
Review Article
DOI:
https://doi.org/10.1530/RAF-21-0105
Volume/Issue:
Volume 3: Issue 3
Open access
Michael L Power Center for Species Survival, Smithsonian’s National Zoo and Conservation Biology Institute, Washington, District of Columbia, USA

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Carly R Muletz-Wolz Center for Conservation Genomics, Smithsonian’s National Zoo and Conservation Biology Institute, Washington, District of Columbia, USA

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Sally L Bornbusch Center for Conservation Genomics, Smithsonian’s National Zoo and Conservation Biology Institute, Washington, District of Columbia, USA
Department of Nutrition Science, Smithsonian’s National Zoo and Conservation Biology Institute, Washington, District of Columbia, USA

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://doi.org/10.1016/j.cobeha.2015.07.008 ) Arroyo R Martín V Maldonado A Jiménez E Fernández L & Rodríguez JM 2010 Treatment of infectious mastitis during lactation: antibiotics versus oral administration of Lactobacilli isolated from breast milk

Article Type:
Review Article
DOI:
https://doi.org/10.1530/RAF-23-0056
Volume/Issue:
Volume 5: Issue 2
Open access