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delivery (term = 250 and preterm = 50), we examined its potential to identify metabolic features associated with spontaneous PTD (sPTD) and microbiota community state types (CST). CSTs were determined for 83 of these samples by sequencing the V1–V3 region
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. 2017 ). The vaginal microbiota at late gestation is similar to that of a non-pregnant (non-menstruating and bacterial vaginosis, BV-negative) state characterised by a decrease in α-diversity (species richness – within individual diversity or amount of
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Centre for Functional Biodiversity, School of Life Sciences, University of KwaZulu-Natal, Pietermaritzburg, South Africa
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and establishment of the gut microbiome in arctic shorebirds . FEMS Microbiology Ecology 93 . ( https://doi.org/10.1093/femsec/fix142 ) Grond K Sandercock BK Jumpponen A & Zeglin LH 2018 The avian gut microbiota: community, physiology and
Division of Biological Sciences, University of California San Diego, La Jolla, California, USA
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Department of Bioengineering, University of California, San Diego, La Jolla, California, USA
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Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, California, USA
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Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, California, USA
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Center for Microbiome Innovation, University of California San Diego, La Jolla, California, USA
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Center for Microbiome Innovation, University of California San Diego, La Jolla, California, USA
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Medical Scientist Training Program, University of California San Diego, La Jolla, California, USA
Division of Gastroenterology, University of California San Diego, La Jolla, California, USA
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, La Jolla, California, USA
Center for Microbiome Innovation, University of California San Diego, La Jolla, California, USA
Jennifer Moreno Department of Veterans Affairs Medical Center, La Jolla, California, USA
Institute of Diabetes and Metabolic Health, University of California San Diego, La Jolla, California, USA
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Department of Bioengineering, University of California, San Diego, La Jolla, California, USA
Center for Microbiome Innovation, University of California San Diego, La Jolla, California, USA
Department of Computer Science and Engineering, University of California, San Diego, La Jolla, California, USA
Halıcıoğlu Data Science Institute, University of California San Diego, La Jolla, California, USA
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-specific disease. The vaginal microbiota’s community composition has been classified into five unique community state types (CSTs), several of which are dominated by lactic acid-producing bacteria belonging to the Lactobacillus genus ( Ravel et al. 2011 , Kwon
Department of Animal Science, University of Wyoming, Laramie, Wyoming, USA
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piglets with lower weight gain (i.e. decreased milk consumption). Interestingly, administering an in-feed probiotic to sows during gestation altered the dam GIT microbiome and the microbiota of the piglets born, suggesting an apparent link between the
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in altering MMP activity for both labour and CIN/cancer The normal vaginal microbiota is dominated by lactobacilli and exhibits low immunostimulatory capacity in pregnant and non-pregnant state ( Amabebe & Anumba 2018 , 2020 ). An altered vaginal
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Department of Internal Medicine, Ponce Health Sciences University, Ponce, Puerto Rico, USA
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. 2018 a, b ). Metabolomics is the study of small molecules within biofluids or tissues and gives information about the physiological state of a cell tissue or biofluid ( EVAR Workgroup et al. 2011 , Goulidelmos et al. 2020 ). Different types of
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IMT International Limited, Tattenhall, Chester, UK
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Chester Zoo, Upton-by-Chester, UK
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found in isolated or inaccessible locations, making sample acquisition and transport both difficult and expensive ( Ryder & Onuma 2018 , Houck 2019 ). However, the global zoo and aquarium community represent a unique resource for samples, either through