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Kate Anthony Department of Animal Science, The Pennsylvania State University, University Park, Pennsylvania, USA

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Tyler Bruce Garner Department of Animal Science, The Pennsylvania State University, University Park, Pennsylvania, USA
Integrative and Biomedical Physiology Program, Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, USA

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Ramesh Ramachandran Department of Animal Science, The Pennsylvania State University, University Park, Pennsylvania, USA
Integrative and Biomedical Physiology Program, Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, USA

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Francisco Javier Diaz Department of Animal Science, The Pennsylvania State University, University Park, Pennsylvania, USA
Integrative and Biomedical Physiology Program, Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, USA

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Introduction Genetic selection for growth rate, feed intake, feed conversion, and meat yield of broiler breeder (BB) lines has led to an increase in hen growth by over four-fold since 1957 ( Zuidhof et al. 2014 ). Consequently, this genetic

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Christina M Merkley Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA

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Allison N Renwick Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA

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Sydney L Shuping Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA

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KaLynn Harlow Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA

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Jeffrey R Sommer Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA

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Casey C Nestor Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA

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experimental design for this study is depicted in Fig. 1A . Briefly, 14 wethers were divided into one of two groups: fed to maintain body weight (FM; n = 6) or feed-restricted to lose body weight (FR; n = 8). Based on previous reports in sheep ( Foster

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Chinwe U Nwachukwu School of Veterinary Medicine and Science, Sutton Bonington campus, The University of Nottingham, Loughborough, Leicestershire, UK
Department of Agricultural Science, School of Agriculture and Vocational Studies, Alvan Ikoku Federal College of Education, Owerri, Imo State, Nigeria

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Kathryn J Woad School of Veterinary Medicine and Science, Sutton Bonington campus, The University of Nottingham, Loughborough, Leicestershire, UK

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Nicole Barnes School of Veterinary Medicine and Science, Sutton Bonington campus, The University of Nottingham, Loughborough, Leicestershire, UK
Medivet Oxted, Oxted, UK

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David S Gardner School of Veterinary Medicine and Science, Sutton Bonington campus, The University of Nottingham, Loughborough, Leicestershire, UK

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Robert S Robinson School of Veterinary Medicine and Science, Sutton Bonington campus, The University of Nottingham, Loughborough, Leicestershire, UK

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balance of cell proliferation to apoptosis ( Lea et al. 2006 ) and diminished oxidative stress response ( Murdoch et al. 2003 , Bernal et al. 2010 ), including in response to restricted protein ( Sui et al. 2014 a , b ). The establishment of an

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Synneva Hagen-Lillevik Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, USA
Department of Nutrition and Integrative Physiology, University of Utah College of Health, Salt Lake City, Utah, USA

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John S Rushing Divisions of Reproductive Sciences, Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Colorado Denver (AMC), Aurora, Colorado, USA

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Leslie Appiah Division of General Obstetrics and Gynecology, Department of Obstetrics and Gynecology, University of Colorado Denver (AMC), Anschutz Outpatient Pavilion, Aurora, Colorado, USA

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Nicola Longo Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, USA
Department of Nutrition and Integrative Physiology, University of Utah College of Health, Salt Lake City, Utah, USA

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Ashley Andrews Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, USA

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Kent Lai Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, USA
Department of Nutrition and Integrative Physiology, University of Utah College of Health, Salt Lake City, Utah, USA

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Joshua Johnson Divisions of Reproductive Sciences, Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Colorado Denver (AMC), Aurora, Colorado, USA

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gene ( Pyhtila et al. 2015 ). Initial symptoms for infants include emesis and poor feeding with failure to thrive, lethargy, jaundice, liver failure, and Gram-negative sepsis. Infants who survive the acute presentation or are treated early because of

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Sharon R Ladyman Centre for Neuroendocrinology and Department of Anatomy, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand
Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand

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Caroline M Larsen Centre for Neuroendocrinology and Department of Anatomy, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand

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Rennae S Taylor Department of Obstetrics and Gynaecology, Faculty of Medical and Health Science, University of Auckland, Auckland, New Zealand

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David R Grattan Centre for Neuroendocrinology and Department of Anatomy, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand
Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand

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Lesley M E McCowan Department of Obstetrics and Gynaecology, Faculty of Medical and Health Science, University of Auckland, Auckland, New Zealand

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Augustine RA Ladyman SR Grattan DR 2008 From feeding one to feeding many: hormone-induced changes in bodyweight homeostasis during pregnancy . Journal of Physiology 586 387 – 397 . ( https://doi.org/10.1113/jphysiol.2007.146316 ) 18033810 Baeyens

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Michael L Power Center for Species Survival, Smithsonian’s National Zoo and Conservation Biology Institute, Washington, District of Columbia, USA

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Carly R Muletz-Wolz Center for Conservation Genomics, Smithsonian’s National Zoo and Conservation Biology Institute, Washington, District of Columbia, USA

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Sally L Bornbusch Center for Conservation Genomics, Smithsonian’s National Zoo and Conservation Biology Institute, Washington, District of Columbia, USA
Department of Nutrition Science, Smithsonian’s National Zoo and Conservation Biology Institute, Washington, District of Columbia, USA

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Introduction Lactation, the maternal production of milk to feed to offspring, is an ancient adaptation of the mammalian lineage. It originated in a synapsid lineage of amniotes approximately 300 million years ago, a few tens of millions of

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Lucy A Bartho School of Pharmacy and Medical Science, Griffith University, Gold Coast Campus, Southport, Queensland, Australia

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Joshua J Fisher Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia

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Sarah L Walton School of Biomedical Sciences, University of Queensland, St. Lucia, Queensland, Australia

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Anthony V Perkins School of Pharmacy and Medical Science, Griffith University, Gold Coast Campus, Southport, Queensland, Australia

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James S M Cuffe School of Biomedical Sciences, University of Queensland, St. Lucia, Queensland, Australia

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Committee (AEC 484/09 and 496/12) and were conducted in accordance with the Australian Code of Practice for the Care and Use of Animals for Scientific Purposes. Animal procedures, including mating, feeding and tissue collection have been previously described

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John D West Section of Obstetrics and Gynaecology, Clinical Sciences, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK

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Clare A Everett Section of Obstetrics and Gynaecology, Clinical Sciences, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK

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-III, abnormal (usually trisomic) cells are present in both the ICM and trophectoderm lineages, so they almost certainly exist before these two lineages segregate and are later excluded from the fetal lineage. In CPM-I, abnormal cells become restricted to the

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Gisele Montano SeaWorld and Busch Gardens Species Preservation Laboratory, SeaWorld Parks and Entertainment Inc., Orlando, Florida, USA

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Pat Clough Dolphin Research Center, Grassy Key, Florida, USA

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Todd Schmitt SeaWorld Parks and Entertainment Inc., SeaWorld California, San Diego, California, USA

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Michelle Davis SeaWorld Parks and Entertainment Inc., SeaWorld Florida, Orlando, Florida, USA

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Karen Steinman SeaWorld and Busch Gardens Species Preservation Laboratory, SeaWorld Parks and Entertainment Inc., Orlando, Florida, USA

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Justine O’Brien SeaWorld and Busch Gardens Species Preservation Laboratory, SeaWorld Parks and Entertainment Inc., Orlando, Florida, USA

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Todd Robeck SeaWorld and Busch Gardens Species Preservation Laboratory, SeaWorld Parks and Entertainment Inc., Orlando, Florida, USA

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into the coelomic cavity of a fish just prior to feeding. Serum progesterone was determined at the start of altrenogest to ensure that none of the females had ovulated. Artificial inseminations ( n   = 11) were performed on all females that developed

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