Behavioural switching during oscillations of intracellular Ca2+ concentration in free-swimming human sperm

in Reproduction and Fertility
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  • 1 E Torrezan-Nitao, University of Birmingham School of Biosciences, Birmingham, B15 2TT, United Kingdom of Great Britain and Northern Ireland
  • 2 H Guidobaldi, Centro de Biologia Celular y Molecular, Universidad Nacional de Cordoba, Cordoba, X5016GCA, Argentina
  • 3 L Giojalas, School of Biology, Universidad Nacional de Córdoba, Córdoba, 5016GCA, Argentina
  • 4 C Barratt, University of Dundee, Dundee, DD1 9sy, United Kingdom of Great Britain and Northern Ireland
  • 5 S Publicover, Biosciences, University of Birmingham, Birmingham, B15 2TT, United Kingdom of Great Britain and Northern Ireland

Correspondence: Stephen Publicover, Email: s.j.publicover@bham.ac.uk

Repetitive [Ca2+]i transients (oscillations), observed in progesterone (P4)-stimulated immobilised human sperm, reversibly modifiy flagellar beating. Here we report that such oscillations also occur in P4-stimulated free-swimming sperm and regulate (or contribute to) behavioural switching.

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